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Table 1 Study participant demographics

From: Reserve-related activities and MRI metrics in multiple sclerosis patients and healthy controls: an observational study

Variable

HC

CIS

RRMS

SPMS

Test Statistic

P-value

P-valueª

N

276

65

352

109

   

Gender: % female

60.87

61.54

64.77

61.47

2.97

0.81

 

Mean Age (sd)

46.93 (15.76)

39.38 (10.99)

44.17 (10.75)

53.91 (8.69)

23.62

0.00

***

Mean Age at Diagnosis (sd)

NA

36.25 (10.92)

34.90 (9.41)

36.21 (10.09)

1.03

0.36

 

Median EDSS (IQR)

NA

1.50 (1–2)

2 (3–1.5)

6 (5–6.5)

24.64

0.00

***

Diease Duration: mean no. years (sd)

NA

5.65 (3.32)

13.1 (7.11)

21.85 (9.10)

83.61

0.00

***

 Range

NA

3–20

2–41

5–45

   

Mean Body Mass Index (sd)

27.31 (5.70)

27.14 (5.86)

27.40 (5.93)

26.10 (6.01)

1.35

0.26

 

Employment Status %

    

201.79

0.00

***

 Full-time

48.22

61.9

45.38

11.32

   

 Part-time

15.81

11.11

12.14

10.38

   

 Homemaker

3.16

7.94

3.47

4.72

   

 Student

7.91

4.76

2.02

0

   

 Unemployed

8.3

6.35

6.65

5.66

   

 Retired

13.83

3.17

6.65

24.53

   

 Disabled

0

3.17

21.97

41.51

   

 Other

2.77

1.59

1.73

1.89

   

Education %

    

30.85

0.01

*

 High school not completed

1.99

1.59

3.78

7.55

   

 Graduated high school

15.54

12.7

17.15

21.7

   

 Some college/Associate/Technical Degree

34.66

38.1

36.05

33.96

   

 Bachelor’s degree

25.9

30.16

23.26

19.81

   

 Graduate/Post-graduate

21.91

17.46

19.77

16.98

   

Race %

    

39.52

0.00

***

 Caucasian

83.59

92.06

91.91

95.28

   

 Hispanic/Latino

1.56

95.24

2.02

0.94

   

 Black/African-American

8.59

98.41

4.91

2.83

   

 Asian

3.91

100

0.58

0

   

 American Indian/Alaska Native

0.39

0

0

0

   

 Other

1.95

0

0.58

0.94

   

Past reserve-related Activities: Mean (sd)

6.60 (0.13)

6.44 (1.76)

6.27 (2.06)

5.75 (2.04)

4.39

0.00

***

 Range

2–10

3–10

2–10

2–10

   

Strenuous reserve-related Activities: Mean (sd)

1.61 (0.078)

0.70 (0.67)

0.64 (0.70)

0.36 (0.41)

76.73

0.00

***

 Range

0–5.42

0–2.83

0–3.23

0–1.8

   

Non-Strenuous reserve-related Activities : Mean(sd)

5.80 (0.16)

5.18 (2.47)

5.36 (2.62)

5.53 (2.84)

1.64

0.18

 

 Range

0.5–12.67

0–12

0–13.5

0–12.83

   
  1. ªHC Healthy Control, CIS Clinically Isolated Syndrome, RRMS Relapsing Remitting MS, SPMS Secondary Progressive MS, The F-Statistics and P-values shown are from tests for differences between disease group for the given variable
  2. * p < 0.05; ** p < 0.01; *** p < 0.001