Table 3 Comparison of concentration of neuro-biochemicals among three groups
From: Case control study: magnetic resonance spectroscopy of brain in HIV infected patients
Variable | Healthy controls | Asymptomatic HIV | HIV with CNS lesion | p-value | Post-hoc comparison | ||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | I vs II | I vs III | II vs III |
| Â | Group 1 | Group 2 | Group 3 | Â | Â | Â | Â |
|  | n = 30 (mmol/kg) | n = 20 (mmol/kg) | n = 21 (mmol/kg) |  |  |  |  |
tNAA | Â | Â | Â | Â | Â | Â | Â |
Frontal | 9.29 ± 3.11 | 10.67 ± 3.8 | 10.99 ± 4.11 | 0.24 | 0.56 | 0.44 | 1 |
Basal ganglia | 7.31 ± 0.47 | 7.29 ± 0.74 | 6.71 ± 0.64 | 0.01 | 1 | 0.01 | 0.03 |
Lip09 + MM09 |  |  |  |  |  |  |  |
FWM | 5.59 ± 1.56 | 5.14 ± 1.79 | 8.69 ± 2.96 | 0.02 | 1 | 0.04 | 0.11 |
BG | 5.87 ± 1.05 | 5.76 ± 1.95 | 5.59 ± 0.53 | 0.78 | 1 | 1 | 1 |
tCho | Â | Â | Â | Â | Â | Â | Â |
FWM | 2.08 ± 0.70 | 2.50 ± 0.99 | 2.62 ± 0.78 | 0.07 | 0.26 | 0.12 | 1 |
BG | 1.62 ± 0.17 | 1.68 ± 0.28 | 1.56 ± 0.16 | 0.27 | 1 | 1 | 0.33 |
tCr | Â | Â | Â | Â | Â | Â | Â |
Frontal | 6.95 ± 2.56 | 8.9 ± 2.9 | 9.14 ± 3.04 | 0.02 | 0.05 | 0.05 | 1 |
Basal ganglia | 6.95 ± 1.51 | 6.3 ± 1.77 | 6.62 ± 0.78 | 0.19 | 0.4 | 0.38 | 1 |
Glx (Glu + Gln) |  |  |  |  |  |  |  |
FWM | 15.0 ± 6.06 | 17.08 ± 5.6 | 20.4 ± 7.8 | 0.05 | 0.82 | 0.05 | 0.47 |
BG | 13.99 ± 2.89 | 14.12 ± 3.6 | 13.92 ± 1.67 | 0.98 | 1 | 1 | 1 |