From: REM sleep behavior disorder was associated with Parkinson’s disease: a community-based study
Scale | REM Sleep Behavior disorder Screening questionnaire (RBDSQ) [12] | Validation of RBDSQ in China [16] | Mayo Sleep Questionnaire (MSQ) [17] | REM Sleep Behavior Disorder Questionnaire–Hong Kong (RBDQ-HK) [13] | Validation of RBDQ-HK in east China [15] | RBD Single-Question Screen (RBD1Q) [7] | Innsbruck REM Sleep Behavior Disroder Inventory (RBD-I) [14] | Chinese version of RBD1Q (RBD1Q-C) |
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No. of items | 13 items | - | 1 screening question on RBD (plus 5 additional questions if screened positive) | 13 questions (Or use the Factor 2 behavioral subscale, which contains 7 questions) | - | 1 question | 5 questions | 1 question |
Informants | Patient, bed partner encouraged | - | Bed partner only | Patient and/or bed partner | - | Patient, spouse/Caregiver encouraged | Patient, bed partner encouraged | Patient, bed partner encouraged |
Validation study | ||||||||
Study cases | n = 54 Idiopathic RBD RBD co-morbid with narcolepsy | n = 63 Idiopathic RBD RBD associated with PD | n = 81 RBD co-morbid with cognitive impairment/neurodegenerative diseases | n = 107 Idiopathic RBD RBD co-morbid with narcolepsy/neurodegenerative diseases | n = 115 Idiopathic RBD, RBDassociated with PD, RBD like disorder | n = 242 Idiopathic RBD | n = 70 Idiopathic RBD RBD co-morbid with narcolepsy/neurodegenerative diseases | n = 14 Idiopathic RBD RBD co-morbid with neurodegenerative diseases |
Study controls | Sleep patients (n = 160) Healthy subjects (n = 133) | Sleep patients (n = 78) PD patients without RBD (n = 35) Healthy subjects (n = 50) | Patients mostly with cognitive impairment/Parkinson’s disease (n = 66) | Sleep patients (n = 86) Psychiatric patients (n = 6) Healthy subjects (n = 15) | Sleep patients(n = 124) Patients with neurogenerative disorder(n = 74) Healthy subjects(n = 12) | Sleep patients and healthy control (total n = 242) | Sleep patients(total = 140) | Sleep patients and healthy control (total n = 32) |
Diagnostic methods | RBD patients & sleep patients: PSG. Healthy subjects: Medical history only, no PSG | PSG | PSG | PSG | PSG | PSG | PSG | PSG |
Psychometric properties | ||||||||
Cut-off | 5/13 | 5/13 | - | 19/100 for total scale and 8/70 for Factor 2 subscale | 17/100 for total scale and 7 or 8/70 for Factor 2 subscale | - | 0.25 (number of positive symptoms divided by number of answered questions) | - |
Sensitivity/Specificity | 96 %/56 % | 92.1 %/81.2 % | 98 %/74 % | 82.2 %/86.9 % 87.9 %/81.3 %(subscale) | 85 %/81 % 90 %/82 %(subscale) | 93.8 %/87.2 % | 91.4 %/85.7 % | 100 %/55.6 % |