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Table 3 Cardiovascular health components, group sizes, and dementia risk. Results of the Cox proportional hazards regressions

From: Predicting dementia in primary care patients with a cardiovascular health metric: a prospective population-based study

Cardiovascular health component scoresa

Dementia/total

N

Unadjusted models

HR (95 % CI)

Adjusted modelsb

HR (95 % CI)

Smoking

 2 (ideal)

214/2366

Reference

Reference

 1 (moderate)

61/821

0.84 (0.63–1.12)

1.15 (0.83–1.61)

 0 (poor)

21/360

0.66 (0.42–1.03)

1.77 (1.09–2.85)

Physical activity

 2 (ideal)

89/1672

Reference

Reference

 1 (moderate)

126/1384

1.80 (1.37–2.36)

1.38 (1.05–1.81)

 0 (poor)

81/491

3.53 (2.61–4.76)

1.81 (1.32–2.47)

Body mass index

 2 (ideal)

99/980

Reference

Reference

 1 (moderate)

141/1645

0.82 (0.64–1.07)

0.98 (0.76–1.28)

 0 (poor)

56/922

0.58 (0.42–0.81)

0.77 (0.55–1.07)

Blood pressure

 2 (ideal)

9/182

Reference

Reference

 1 (moderate)

122/1460

1.76 (0.90–3.47)

0.90 (0.46–1.79)

 0 (poor)

165/1905

1.83 (0.93–3.57)

0.74 (0.37–1.45)

Total cholesterol

 2 (ideal)

88/911

Reference

Reference

 1 (moderate)

130/1613

0.82 (0.63–1.08)

0.81 (0.62–1.06)

 0 (poor)

78/1023

0.78 (0.58–1.06)

0.86 (0.63–1.16)

Fasting glucose

 2 (ideal)

197/2511

Reference

Reference

 1 (moderate)

59/689

1.10 (0.82–1.47)

0.84 (0.63–1.13)

 0 (poor)

40/347

1.57 (1.12–2.20)

1.43 (1.02–2.02)

  1. Boldface indicates statistical significance at p < 0.05. aHigher scores indicate better cardiovascular health. bAdjusted for age, sex, and education. HR hazard ratio. 95 % CI 95 % confidence interval