Fig. 1

Volumetric MRI analysis of our patient’s (dark arrow) hippocampus and parietal lobe compared to AD patients and age-matched healthy controls after intracranial-volume correction. Z-scores of hippocampal and parietal lobe volume compared to healthy controls were −2.9 and −4.2 respectively. Our patient’s datapoint lay within the 95 % confidence region of Alzheimer’s disease and outside the 95 % confidence region of healthy controls and was therefore automatically assigned to the Alzheimer’s disease group