Fig. 3From: Study design of PANGAEA 2.0, a non-interventional study on RRMS patients to be switched to fingolimodIndividual treatment concept NEDA- 4 (no evidence of disease activity-4). This new treatment concept comprises the criteria relapse rate, MRI activity, loss of brain volume, and disability progression (EDSS: Expanded Disability Status Scale). Individual treatment objective, "No evidence of dicease activity-4" (NEDA-4)Back to article page