Table 1 Demographic characteristics and risk factors for neuropathy in patients with Parkinson’s disease and Parkinsonism
From: Small (autonomic) and large fiber neuropathy in Parkinson disease and parkinsonism
Parkinson’s disease (N = 38) | Parkinsonism (N = 16) | |
|---|---|---|
Age | 63 ± 2.1 | 50.1 ± 3.9* |
% Female | 26.3 | 43.8 |
Age of onset (years) | 54.3 ± 2 | 42.1 ± 4.3 |
Disease duration (years) | 8 ± 0.8 | 6.9 ± 1.1 |
Definite and Possible Risk Factors for Neuropathy | ||
% Diabetes mellitus | 10.5 | 25 |
% Thyroid disease | 6.6 | 0 |
% B12 level <200 | 13 | 22.2 |
% B12 level <300 | 20.8 | 44.4 |
% Levodopa use | 97.2 | 68.8 |
Neurophysiological studies | ||
Peroneal CMAP (mV) | 3.99 ± 0.47 | 3.8 ± 0.66 |
Peroneal CV (m/s) | 46.9 ± 1.02 | 49.3 ± 1.56 |
SNAP (μV) | 11.9 ± 1.16 | 14.5 ± 3.77 |
Sural CV (m/s) | 48.9 ± 0.88 | 46.3 ± 1.12 |
Tibial CMAP (mV) | 8.67 ± 0.88 | 9.8 ± 1.3 |
Tibial CV (m/s) | 47 ± 0.76 | 46.2 ± 1 |