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Table 1 Demographic characteristics and risk factors for neuropathy in patients with Parkinson’s disease and Parkinsonism

From: Small (autonomic) and large fiber neuropathy in Parkinson disease and parkinsonism

  Parkinson’s disease (N = 38) Parkinsonism (N = 16)
Age 63 ± 2.1 50.1 ± 3.9*
% Female 26.3 43.8
Age of onset (years) 54.3 ± 2 42.1 ± 4.3
Disease duration (years) 8 ± 0.8 6.9 ± 1.1
Definite and Possible Risk Factors for Neuropathy
 % Diabetes mellitus 10.5 25
 % Thyroid disease 6.6 0
 % B12 level <200 13 22.2
 % B12 level <300 20.8 44.4
 % Levodopa use 97.2 68.8
Neurophysiological studies
 Peroneal CMAP (mV) 3.99 ± 0.47 3.8 ± 0.66
 Peroneal CV (m/s) 46.9 ± 1.02 49.3 ± 1.56
 SNAP (μV) 11.9 ± 1.16 14.5 ± 3.77
 Sural CV (m/s) 48.9 ± 0.88 46.3 ± 1.12
 Tibial CMAP (mV) 8.67 ± 0.88 9.8 ± 1.3
 Tibial CV (m/s) 47 ± 0.76 46.2 ± 1
  1. *P < 0.05, Student t test