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Table 6 Univariable and multivariable analyses of factors associated with cognitive disorders after acute ischemic stroke

From: Association between serum non-high-density lipoprotein cholesterol and cognitive impairment in patients with acute ischemic stroke

  Univariable Multivariable
Variables P OR 95 % CI P OR 95 % CI
Gender, male 0.239 0.729 0.431–1.234    
Age 0.001 1.043 1.018–1.068 0.001 1.039 1.016–1.064
BMI 0.623 0.982 0.913–1.056    
Years of education <0.001 0.817 0.772–0.866 <0.001 0.808 0.757–0.861
Hypertension 0.324 1.207 0.831–1.755    
Diabetes <0.001 1.276 1.175–1.385 0.341 1.400 0.700–2.797
Coronary heart disease 0.388 1.380 0.664–2.870    
History of smoking 0.367 1.226 0.788–1.907    
History of drinking 0.524 1.221 0.661–2.254    
Family history of dementia 0.001 1.219 1.082–1.374 0.055 0.242 0.057–1.031
History of stroke 0.021 1.742 1.087–2.791 0.025 1.723 1.071–2.771
High TC 0.629 0.791 0.306–2.044    
High TG 0.674 1.078 0.760–1.529    
Low HDL-C 0.088 0.650 0.396–1.066    
High LDL-C 0.900 1.025 0.694–1.514    
High Non-HDL-C 0.034 3.115 1.088–8.917 <0.001 3.115 1.088–8.917
Normal level 0.170 1.691 0.799–3.579 0.088 1.691 0.799–3.579
Higher than normal 0.046 2.710 1.017–7.221 0.052 2.710 1.017–7.221
Critical high level 0.026 5.877 1.231–28.065 0.040 5.877 1.231–28.065
Very high level 0.013 7.006 1.502–32.675 0.932 7.006 1.502–32.675
High Hcy <0.001 1.060 1.032–1.088 <0.001 1.057 1.031–1.084
hsCRP 0.515 0.990 0.960–1.021    
Fasting hyperglycemia [n (%)] 0.285 1.084 0.935–1.256    
High HbA1c 0.960 1.002 0.939–1.068    
NPI 0.218 1.039 0.978–1.104    
HAMD-21 0.001 1.224 1.089–1.375 0.001 1.284 1.177–1.401
ADL 0.141 1.012 0.996–1.029    
  1. BMI body mass index, Non-HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, HCY homocysteine, hsCRP serum high-sensitivity C-reactive protein, HbA1c glycated hemoglobin, MMSE mini-mental state examination, MoCA Montreal Cognitive Assessment, NPI Neuropsychiatric Inventory, ADL Activity of Daily Living Scale, HADM-21 Hamilton depression rating scale 21-item