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Fig. 3 | BMC Neurology

Fig. 3

From: Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice

Fig. 3

Expression of pericyte markers after 30 min MCAo/reperfusion. a-c mRNA transcription of pericyte-related molecules was measured in ischemic brain tissue of wildtype and VE-cadherin heterozygous mice after 30 min MCAo/reperfusion. Relative mRNA expression is reported as the value normalized to tripeptidyl peptidase 2 (Tpp2) for each sample. N = 3-6 animals per group. One-way ANOVA, *p < 0.05 versus sham, #p < 0.05 between genotypes within time point. α-SMA (alpha-smooth muscle actin), CD13 (aminopeptidase N), PDGFR-β (platelet derived growth factor receptor-β). d Increased pericyte coverage of vasculature in the ischemic brain of VEC+/- mice at 28 days after MCAo. Green: GLUT-1. Red: desmin. Scale bar 50 μm

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