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Table 3 Association between SNPs and LAA using the additive, genotype, dominant, and the recessive models

From: Association study of polymorphisms in the ABO gene with ischemic stroke in the Chinese population

SNP

Model

Allele or geno

case

control

Unadjusted OR (95 % CI)

Unadjusted

p-value

Adjusted

OR (95 % CI)

Adjusted p-value

rs579459

Additive

C/T

197/721

334/1576

1.29 (1.06-1.57)

0.01

1.27 (1.00-1.61)

0.047

 

Dominant

CC + CT/TT

174/285

300/655

1.33 (1.06-1.68)

0.015

1.28 (0.96-1.70)

0.09

 

Recessive

CC/CT + TT

23/436

34/921

1.43 (0.83-2.46)

0.19

1.70 (0.88-3.29)

0.11

rs651007

Additive

T/C

193/703

337/1575

1.28 (1.05-1.56)

0.01

1.30 (1.02-1.64)

0.033

 

Dominant

TT + CT/CC

170/278

304/652

1.31 (1.04-1.66)

0.02

1.29 (0.97-1.71)

0.08

 

Recessive

TT/CT + CC

23/425

33/923

1.51 (0.88-2.61)

0.13

1.89 (0.97-3.65)

0.06

rs529565

Additive

C/T

374/518

709/1201

1.22 (1.04-1.44)

0.01

1.24 (1.02-1.51)

0.03

 

Dominant

CC + CT/TT

295/151

565/390

1.35 (1.07-1.71)

0.01

1.39 (1.05-1.84)

0.02

 

Recessive

CC/CT + TT

79/367

144/811

1.21 (0.90-1.64)

0.21

1.24 (0.86-1.79)

0.25

  1. All SNPs were analyzed under additive, genotype, dominant (Dom) and recessive (Rec) models; OR: odds ratio; CI: confidence interval; unadjusted P-value from t-test; adjusted P-value using logistic regression analysis with age, gender, hypertension, diabetes, and dyslipidemia as covariates. Significant P values (p < 0.05) are in bold and p* < 0.017 (Bonferroni multiple correction threshold)