Table 2 Pregnancy outcome categorized by time of discontinuation of natalizumab
Outcome of pregnancy, n (%) | Before conception (n = 73) | First trimester (n = 275) | Second trimester (n = 10) | Third trimester (n = 1) | Continued during pregnancy (n = 4) | Total (N = 363) |
|---|---|---|---|---|---|---|
Spontaneous abortions | 0 | 32 (11.6) | 0 | 0 | 0 | 32 (8.8) |
Elective termination (fetal defects) | 1 (1.4) | 0 | 0 | 0 | 0 | 1 (0.3) |
Elective termination (no fetal defects or unknown) | 2 (2.7) | 11 (4.0) | 0 | 0 | 0 | 13 (3.6) |
Stillbirths without fetal defects | 1 (1.4) | 0 | 0 | 0 | 0 | 1 (0.3) |
Live birth with congenital anomaly | 7 (9.6)a | 22 (8.0)b | 0 | 0 | 0 | 29 (8.0) |
Live birth without congenital anomaly | 62 (84.9)c | 210 (76.4)a | 10 (100) | 1 (100) | 4 (100) | 287 (79.1) |