Skip to main content

Table 1 Demographic and clinical characteristics of patients with sporadic amyotrophic lateral sclerosis and controls with non-ALS neurological disorders

From: Assessment of a multiple biomarker panel for diagnosis of amyotrophic lateral sclerosis

Characteristic ALS (n = 40) Controls (n = 40)
Male, n (%) 26 (55) 24 (60)
Age, yr 52.08 ± 11.45 53.68 ± 11.93
Age at onset, yr 57.96 ± 10.96  
Disease duration, mo 17.61 (2.77–50.43)  
Site of onset (spinal/bulbar), n 33/7  
ALSFRS-R score 38.32 (21–47)  
Progression rate 0.91 (0.08–5.06)  
Rapidly progressive (progression rate > 0.91/month)/Slowly progressive (progression rate ≤ 0.91/month) 12/28  
Annual decline of ALSFRS 11.01 (3.10–33.31)  
Monthly decline of ALSFRS 0.92 (0.26–2.78)  
Rapidly worsening 0.92/month)/ 10/16  
Slowly worsening (monthly decline of ALSFRS-R ≤0.92/month) 26/11/3  
Survival/death/ lost to follow-up 26/11/3  
  1. Values shown are n, n (%), mean ± SD, or median (range)
  2. ALSFRS-R, Amyotrophic Lateral Sclerosis Functional Scale - Revised