Table 1 Demographic and clinical characteristics of patients with sporadic amyotrophic lateral sclerosis and controls with non-ALS neurological disorders
From: Assessment of a multiple biomarker panel for diagnosis of amyotrophic lateral sclerosis
Characteristic | ALS (n = 40) | Controls (n = 40) |
|---|---|---|
Male, n (%) | 26 (55) | 24 (60) |
Age, yr | 52.08 ± 11.45 | 53.68 ± 11.93 |
Age at onset, yr | 57.96 ± 10.96 | |
Disease duration, mo | 17.61 (2.77–50.43) | |
Site of onset (spinal/bulbar), n | 33/7 | |
ALSFRS-R score | 38.32 (21–47) | |
Progression rate | 0.91 (0.08–5.06) | |
Rapidly progressive (progression rate > 0.91/month)/Slowly progressive (progression rate ≤ 0.91/month) | 12/28 | |
Annual decline of ALSFRS | 11.01 (3.10–33.31) | |
Monthly decline of ALSFRS | 0.92 (0.26–2.78) | |
Rapidly worsening 0.92/month)/ | 10/16 | |
Slowly worsening (monthly decline of ALSFRS-R ≤0.92/month) | 26/11/3 | |
Survival/death/ lost to follow-up | 26/11/3 |