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Cognitive impairment/dementia
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A cortical dementia may develop in advanced stages
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Usually starts with a subcortical dementia
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Psychotic disorders
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Organic psychosis (basal ganglia calcification); delusion has syndromic pervasiveness behavioral, is moderately structured and organized, has low emotional participation, varied content. Abnormalities of perception are rare.
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Organic psychosis (dementia): delusion is poorly structured and organized, override the contents of jealousy, poisoning, and persecution. Abnormalities of perception are frequent.
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Mood disorders
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May be associated to psychotic symptoms. Depressive disorders are prevalent towards maniacal ones.
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Always associated with cognitive impairment, may precede symptoms as prodromes. Prevailing depression, irritability, hyper-emotionality, apathy
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Anxiety disorders
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Possible association between Fahr’s disease and obsessive-compulsive disorder.
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Possible association between Fahr’s disease and obsessive-compulsive disorder. They can also be associated to cognitive impairment
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Other neuro psychiatric/cognitive disorders
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Possible attention’s disorders.
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Progressive alteration of cognitive functions (attention, language, memory, constructive abilities, etc.)
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Extrapyramidal movement disorders
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In advanced stages of the disease.
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May be present since the onset.
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Response to therapy
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Poor sensibility to neuroleptic treatment; high susceptibility to side effects.
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Poor response to any type of symptomatic therapy. Frequent side effects.
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