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Fig. 5 | BMC Neurology

Fig. 5

From: Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis

Fig. 5

Combination treatment of irradiation and chloroquine have synergistically effects on decreasing the GICs’ tumorsphere numbers and diameters. a-d U87 GICs were treated as described before, then seeded in serum-free medium to generate tumorspheres,5 days after treatment, we counted and photographed total tumorspheres (a control group, b chloroquine group, c radiation group, d conbination group). e Quantitative analysis of the relative tumorsphere numbers treated by indicated treatments. f Quantitative analysis of the diameter of the tumorspheres treated by indicated treatments. (*, p < 0.05, **p < 0.01)

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BMC Neurology

ISSN: 1471-2377

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