| All N = 1782 | Cognitive Normal N = 1437 | MCI N = 345 | P value |
---|---|---|---|---|
Gender, male, n (%) | 818(45.9) | 659(45.9) | 159(46.1) | 0.939 |
Age, years, mean(SD) | 70.1(7.1) | 69.4(6.8) | 73.0(7.8) | <0.0001 |
Education, years, mean(SD) | 12.3(3.9) | 12.8(3.5) | 10.4(4.9) | <0.0001 |
MMSE, scores, mean(SD) | 28.4(1.8) | 28.7(1.5) | 27.0(2.5) | <0.0001 |
OI, scores, mean(SD) | 8.0(2.1) | 8.2(2.0) | 7.1(2.3) | <0.0001 |
Living alone, n (%) | 145(8.2) | 107(7.5) | 38(11.1) | 0.035 |
Cigarette smoking, n (%) | 185(10.4) | 141(9.9) | 44(12.8) | 0.117 |
Alcohol drinking, n (%) | 142(8.0) | 114(8.0) | 28(8.2) | 0.915 |
Heart disease, n (%) | 194(10.9) | 150(10.5) | 44(12.8) | 0.223 |
Hypertension, n (%) | 962(54.0) | 759(52.8) | 203(58.8) | 0.043 |
Diabetes, n (%) | 247(13.9) | 180(12.5) | 67(19.5) | 0.001 |
Anxiety, n (%) | 42(2.4) | 34(2.4) | 8(2.3) | 0.969 |
Depression, n (%) | 277(15.6) | 207(14.4) | 70(20.4) | 0.008 |
APOE-ε4 allele positive, n (%) | 308(18.3) | 251(18.4) | 57(17.9) | 0.837 |