Variable | Model 1 OR (95Â % CI) | P value | Model 2 OR (95Â % CI) | P value |
---|---|---|---|---|
OI (score, decreasing) | 1.18(1.11,1.25) | <0.0001 | 1.19(1.11,1.27) | <0.0001 |
Age (increasing) | 1.05(1.03, 1.07) | <0.0001 | 1.05(1.03, 1.07) | <0.0001 |
Gender (female vs. male) | 0.77(0.60, 1.00) | 0.053 | 0.85(0.63, 1.15) | 0.284 |
Education year (increasing) | 0.88(0.86, 0.91) | <0.0001 | 0.88(0.85, 0.91) | <0.0001 |
Living alone | Â | Â | 1.00(0.63, 1.59) | 0.995 |
Cigarette smoking | Â | Â | 1.57(0.99, 2.47) | 0.053 |
Alcohol drinking | Â | Â | 0.77(0.46, 1.28) | 0.309 |
Heart disease | Â | Â | 0.87(0.57, 1.32) | 0.506 |
Hypertension | Â | Â | 0.98(0.75, 1.29) | 0.896 |
Diabetes | Â | Â | 1.54(1.08, 2.20) | 0.018 |
Anxiety | Â | Â | 0.59(0.25, 1.39) | 0.227 |
Depression | Â | Â | 1.67(1.18, 2.37) | 0.004 |
APOE-ε4 allele positive |  |  | 1.04(0.73, 1.46) | 0.845 |