Table 3 In- and exclusion criteria

Idiopathic Parkinson’s disease diagnosed by a neurologist

Medication affecting cognition (such as anticholinergic drugs, benzodiazepine and methylfenidate)

Hoehn & Yahr stage ≤3

Other medical conditions:

o Advanced problems in cognitive functioning (MoCA <19/30)

o Dementia

o Active depression or psychosis and/or treatment with anti-depressant or anti-psychotic drugs

o History of active thyroid disease, stroke with residual deficits, severe hypertension or diabetes or head trauma interfering in cognition

Age 40-75 years

Severe auditory of visual deficits

Mild cognitive impairment according to MDS (MCI Level 1 criteria)

No internet at home

Relatively stable dopaminergic medication dose for at least three months prior to the study, or change in medication does not influence cognition. Deemed unlikely to start or stop treatment within the next three months.

fMRI sub-study:

o Metal in the body

o Claustrophobia