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Table 1 Patient Characteristics

From: Clinical features, treatment and outcome in neurosarcoidosis: systematic review and meta-analysis

Characteristic

n/Na (%)

Characteristic

n/Na (%)

Age, yr., meanb(SD)

43.1 (11.57)

Neurological symptoms

 

Sex, male

486/1088 (45)

 Headache

271/860 (32)

Ethnicity

 

 Sensory abnormalities

138/484 (29)

 Caucasian

461/739 (62)

  Hypaesthesia

39/174 (22)

 African

218/739 (29)

  Paraesthesia

69/334 (21)

 Other

27/739 (4)

  Neuropathic pain

25/216 (12)

 Unknown

33/739 (4)

 Gait abnormalities

128/466 (28)

Presentation of disease

 

 Visual impairment

105/450 (23)

 History of sarcoidosis

229/728 (31)

 Fatigue

47/202 (23)

 Systemic sarcoidosis at admission

256/440 (58)

 Motor abnormalities

103/552 (19)

 Primary neurological presentation

344/662 (52)

  Hemiparesis

41/454 (9)

 Isolated neurosarcoidosis

169/770 (22)

  Paraparesis

37/348 (11)

Systemic involvement

 

 Ataxia

64/387 (17)

 Pulmonary

316/469 (67)

 Vertigo

39/277 (14)

 Eye

117/469 (25)

 Hearing impairment

97/716 (14)

 Dermatological

99/469 (21)

 Seizures

132/965 (14)

 Rheumatological

99/469 (21)

 Nausea

11/84 (13)

 Otorhinolaryngeal

43/469 (9)

 Diplopia

41/361 (11)

 Hepatic

37/469 (8)

 Micturition abnormalities

23/206 (11)

 Cardial

26/469 (6)

 Dysarthria

36/413 (9)

 Constitutional symptoms

106/469 (23)

 Dysphagia

44/481 (9)

Cranial nerve palsy

572/1047 (55)

 Psychiatric symptoms

30/390 (8)

 n. VII palsy

227/937 (24)

 Nystagmus

11/172 (6)

 n. II palsy

190/910 (21)

 Papilledema

23/354 (6)

 n. V palsy

111/942 (12)

Site of neurological involvement

 

 n. VIII palsy

102/914 (11)

 Spinal cord disease

98/543 (18)

 n. VI palsy

63/906 (7)

 Peripheral neuropathy

97/558 (17)

 n. III palsy

46/869 (5)

  Polyneuropathy

56/487 (11)

 n. IX–X palsy

32/882 (4)

  (Multiple Mononeuropathies)

16/137 (12)

 n. I palsy

17/889 (2)

  Radiculopathy

7/140 (5)

 n. IV palsy

17/869 (2)

 Meningitis

105/648 (16)

 n. XI palsy

5/882 (1)

 Myopathy

43/288 (15)

 n. XII palsy

12/882 (1)

 Neuro-endocrinec

90/1034 (9)

 >1 cranial nerve involved

206/724 (28)

 Hydrocephalus

52/570 (9)

  1. a n/N: number for which a certain characteristic is present out of the total number of patients for which it was described
  2. b The mean age was recalculated from averages presented in 27 studies (967 patients)
  3. c Panhypopituirism (n = 34), Diabetes insipidus (n = 21), amenorrhea (n = 5), hypothermia/hypotension (n = 1), galactorrhoea (n = 1), not further specified (n = 28)