Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40

BMC Neurology

Table 2 Correlations of CSF levels of YKL-40 with CSF Tau/Aβ ratio, AB42, ptau₁₈₁, and tau levels before and after adjusting for top SNP effect

	CSF Tau/Aβ ratio		CSF Aβ₄₂ levels		CSF ptau₁₈₁ levels		CSF tau levels
	p	r	p	r	p	r	p	r
CSF YKL-40	2.61×10^-8	0.318	0.838	0.012	8.98×10^-22	0.521	7.06×10^-22	0.522
CSF YKL-40-rs10399931 effect	5.28×10^-10	0.357	0.972	0.002	2.82×10^-26	0.573	1.66×10^-26	0.575
	p	95 % CI	p	95 % CI	p	95 % CI	p	95 % CI
Correlation difference (Meng Z-test)	0.071	-0.083, 0.003	0.661	-0.031, 0.049	0.006	-0.116, -0.020	0.006	-0.116, -0.020

95 % CI: 95 % confidence interval, null hypothesis was retained if interval included 0

ISSN: 1471-2377