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A step toward essential tremor gene discovery: identification of extreme phenotype and screening of HTRA2 and ANO3

  • Mathilde Renaud1, 2, 3,
  • Christophe Marcel1, 2,
  • Gabrielle Rudolf1, 2, 3,
  • Mickaël Schaeffer2, 4,
  • Ouhaïd Lagha-Boukbiza1, 2,
  • Jean-Baptiste Chanson1, 2,
  • Jamel Chelly2, 3, 5,
  • Mathieu Anheim1, 2, 3 and
  • Christine Tranchant1, 2, 3Email author
BMC NeurologyBMC series – open, inclusive and trusted201616:238

Received: 10 September 2015

Accepted: 10 November 2016

Published: 23 November 2016

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
10 Sep 2015 Submitted Original manuscript
22 Apr 2016 Reviewed Reviewer Report - Anne Grunewald
11 Jul 2016 Author responded Author comments - Mathilde Renaud
Resubmission - Version 2
11 Jul 2016 Submitted Manuscript version 2
20 Jul 2016 Reviewed Reviewer Report - Kuo-Hsuan Chang
11 Aug 2016 Reviewed Reviewer Report - Yi Zhao
12 Sep 2016 Author responded Author comments - Mathilde Renaud
Resubmission - Version 3
12 Sep 2016 Submitted Manuscript version 3
10 Nov 2016 Editorially accepted
23 Nov 2016 Article published 10.1186/s12883-016-0748-3

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Service of Neurology, University Hospital of Strasbourg, Hospital of Hautepierre, Strasbourg Cedex, France
Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM-U964/CNRS-UMR7104/Université de Strasbourg, Illkirch, France
Département d’informations médicales, Hôpitaux universitaires de Strasbourg, Hôpital civil, Strasbourg, France
Service de Diagnostic génétique, Nouvel hôpital civil, Strasbourg Cedex, France