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Table 3 Primary Exposures and Outcomes by ASD Affected or Unaffected status (N = 770)

From: Prevalence of non-febrile seizures in children with idiopathic autism spectrum disorder and their unaffected siblings: a retrospective cohort study

Characteristic variable

ASD (n = 610) # (%)

Unaffected siblings (n = 160) # (%)

F or χ2; p

Non-febrile seizures

 Yes

50 (8.2)

4 (2.5)

χ2(1) = 6.25; 0.01

 No

134 (91.8)

156 (97.5)

Febrile seizures

 Yes

19 (3.1)

5 (3.1)

χ2(1) = 0.0001; 0.99

 No

591 (96.9)

155 (96.9)

Type of non-febrile seizures

 Complex partial

9 (1.5)

1 (0.6)

χ2a

 Generalized/ Grand mal

16 (2.6)

0 (0.0)

 Absence/petit mal

7 (1.1)

1 (0.6)

 Other

6 (1.0)

2 (1.3)

 Unknown

7 (1.1)

0 (0.0)

 Multiple

5 (0.8)

0 (0.0)

 None

560 (91.8)

156 (97.5)

GI dysfunctions

 Yes

251 (42.5)

20 (12.8)

χ2(2) = 45.33; <0.0001

 No

340 (57.5)

136 (87.2)

Type of GI dysfunctions

 Gastroesophageal reflux

12 (2.0)

6 (3.8)

χ2(6) = 57.37; <0.0001

 Irritable bowel syndrome

2 (0.3)

2 (1.3)

 Chronic diarrhea

66 (10.8)

3 (1.9)

 Constipation

86 (14.1)

3 (1.9)

 Other

33 (5.4)

3 (1.9)

 Multiple

52 (8.5)

3 (1.9)

 None

359 (58.9)

140 (87.5)

  1. aStatistics not available due to empty cells