Fig. 1
From: miR-491 regulates glioma cells proliferation by targeting TRIM28 in vitro
miR-491 is reduced in glioma, which is correlated with poor prognosis. a Expression of miR-491 in GBM tissues (n = 20) and control brain tissues (n = 6) tested by RT-qPCR assays. ***P < 0.001 b miR-491 expression is lower in SHG44, U87, U251 glioma cell lines than in control brain tissues. *P < 0.05, **P < 0.01. c Expression of miR-491 in GBM (n = 512) and control brain specimens (n = 10) from TCGA database. Data are shown as median and range. P < 0.0001. d Retrospective analysis of the overall survival from TCGA database demonstrated that decreased miR-491 expression represent poor prognosis in GBM. Cut-off =6.962409973. P = 0.0055