Fig. 2From: miR-491 regulates glioma cells proliferation by targeting TRIM28 in vitroTRIM28 is directly targeted by miR-491. a The nucleotide 57-63 region within the 3’-UTR of TRIM28 are potential complementary site of miR-491. b BibiServ analysis of free energy (DG) for hybridization of miR-491 and 3’-UTR of TRIM28. c A schematic diagram of reporter which contained 3’UTR of TRIM28 was constructed. d Luciferase reporter assays were performed after co-transfecting with pGL3-TRIM28-wt or pGL3-TRIM28-mt alone, or together with miR-491 mimics or scrambled miRNA controls (NS). Data are listed as mean ± SD of three times. ***P < 0.001Back to article page