Fig. 4
From: miR-491 regulates glioma cells proliferation by targeting TRIM28 in vitro
miR-491 inhibits glioma cell proliferation by modulating TRIM28. a U251 and U87 cells were transfected with scrambled microRNA (NC), miR-491 mimics or miR-491 mimics together with pLenti-TRIM28. TRIM28 protein expressions following transfection in U87 and U251 cells were tested by western-blot assay. b MTT assays were performed to detect cell proliferation ability. ***P < 0.001. c and (d) Clone formation ability was decreased following miR-491 transfection, which could be reversed by up-regulation of TRIM28 expression. Data are revealed in mean ± SD of in triplet. *P < 0.05, **P < 0.01, ***P < 0.001