Serum albumin to globulin ratio is related to cognitive decline via reflection of homeostasis: a nested case-control study

Table 2 Logistic regression analysis according to CD condition

	Number		Model I		Model II		Model III
	Control	CD	OR	95% CI	OR	95% CI	OR	95% CI
DWL Baseline
grade 0	67	17	Reference		Reference		Reference
grade 1	44	17	1.476	0.669-3.255	1.684	0.715-3.967	1.451	0.573-3.671
DWL 1st follow-up
grade 0	52	11	Reference		Reference		Reference
grade 1	55	20	1.764	0.754-4.129	1.872	0.759-4.619	1.763	0.697-4.455
grade 2	8	3	1.314	0.620-2.787	1.458	0.598-3.557	1.049	0.299-3.387
DWL 2nd follow-up
grade 0	43	5	Reference		Reference		Reference
grade 1	50	21	3.659	1.242-10.77	4.562	1.382-15.05	4.427	1.323-14.81
grade 2	17	7	2.058	1.042-4.062	3.969	1.424-11.06	4.215	1.384-12.83
grade 3	6	1	1.008	0.450-2.259	0.807	0.273-2.384	1.103	0.274-4.442
PVH Baseline
grade 0	83	23	Reference		Reference		Reference
grade 1	29	11	1.156	0.479-2.791	0.848	0.327-2.197	0.700	0.254-1.930
PVH 1st follow-up
grade 0	66	18	Reference		Reference		Reference
grade 1	41	15	1.152	0.498-2.668	0.971	0.392-2.409	0.909	0.359-2.298
grade 2	8	1	0.591	0.192-1.815	0.611	0.188-1.988	0.632	0.191-2.095
PVH 2st follow-up
grade 0	61	17	Reference		Reference		Reference
grade 1	44	13	0.857	0.354-2.075	0.847	0.337-2.131	0.857	0.337-2.175
grade 2	7	4	1.450	0.716-2.937	1.254	0.554-2.842	1.221	0.524-2.841

ModelI: Adjusted for age and sex
Model II: Adjusted for age, sex, apolipoprotein E4, education, smoking and alcohol drinking habits
Model III: Adjusted for age, sex, apolipoprotein E4, education, smoking and alcohol drinking habits, hypertension, hyperlipidemia and diabetes
CD cognitive decline, DWL white matter lesions, PVH perivascular hyperintensities, OR odds ratio, CI confidence interval

ISSN: 1471-2377