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Table 1 Demographic and clinical characteristics of 23 patients with NMOSD

From: Screening for onconeural antibodies in neuromyelitis optica spectrum disorders

Patient

Anti-AQP4

Clinical characteristics

Malignoma

Associated autoimmune disease

Duration of follow-up (years)

#1

+

ON and LETM

-

Sjögren’s syndrome

4

#2

-

ON and LETM

-

-

3

#3

-

ON and LETM

-

Hashimoto’s thyroiditis

6

#4

+

LETM

-

-

5,5

#5

-

ON and LETM

Astrocytomaa

-

10

#6

+

LETM

-

-

2

#7

-

ON and LETM

-

-

5

#8

-

ON and LETM

-

Hashimoto’s thyroiditis

5

#9

-

ON and LETM

-

-

5

#10

-

ON and LETM

-

Hashimoto’s thyroiditis

9

#11

+

ON and LETM

-

-

0.5

#12

+

LETM

-

Systemic lupus erythematosus

5

#13

+

ON and LETM

-

-

6

#14

-

ON and LETM

-

-

5.5

#15

-

ON and LETM

AML

-

6

#16

+

ON and LETM

-

Sjögren’s syndrome

1

#17

-

ON and LETM

-

-

2

#18

+

ON and LETM

-

-

8

#19

+

ON and LETM

-

Non-differentiated collagenosis

3.5

#20

+

ON and LETM

-

-

8

#21

+

LETM

-

-

0.5

#22

+

LETM

-

Hashimoto's thyroiditis

7

#23

+

ON and LETM

-

-

1

  1. Abbreviations: NMOSD neuromyelitis optica spectrum disorders, AQP4 aquaporin-4, ON optic neuritis, LETM longitudinal extensive transverse myelitis, AML acute myeloid leukemia
  2. aAnaplastic astrocytoma that progressed to secondary glioblastoma