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Table 1 Comparison of clinic characteristics between AS and ASR or AR patients

From: Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients

Parameter

AR + ASR

AS

P-value

n = 220

n = 630

Age (years)

70.8 ± 12.76

70.01 ± 11.35

0.94

Gender (female, %)

122 (55.45)

285 (45.24)

0.02

Body mass index (kg/m2)

23.85 ± 3.34

23.92 ± 3.32

0.99

Current smoking (n, %)

66 (30.00)

182 (28.89)

0.62

Hypertension (n, %)

157 (71.36)

439 (69.68)

0.89

Diabetes (n, %)

79 (35.91)

112 (17.78)

<0.001

Previous MI (n, %)

7 (3.2)

14 (2.2)

0.72

NIHSS score at enrollment

5.91 ± 1.81

5.87 ± 1.86

0.89

TC (mmol/L)

5.32 ± 1.18

5.29 ± 1.76

0.26

TG (mmol/L)

1.80 ± 0.83

1.79 ± 0.90

0.96

HDL-C (mmol/L)

1.32 ± 0.32

1.31 ± 0.33

0.85

LDL-C (mmol/L)

3.13 ± 0.92

2.93 ± 0.86

<0.001

Fasting glucose (mmol/L)

7.21 ± 2.12

6.43 ± 1.86

<0.001

Platelet count (×109/L)

193.01 ± 28.62

196.42 ± 30.46

0.79

Stroke subtype

 Atherothrombotic (n, %)

135 (61.36)

384 (60.95)

0.86

 Small artery disease (n, %)

85 (38.64)

246 (39.05)

0.86

  1. AR aspirin resistance, ASR aspirin semi-resistance, AS aspirin sensitivity, MI myocardial infarction, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, NIHSS National Institutes of Health Stroke Scale