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Table 2 Association of SNPs with responses of aspirin in IS patients (%)

From: Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients

  AR + ASR AS P-value
n = 220 n = 630
COX-1 (rs1236913)
 CC 198 (90.0) 567 (90.0) 0.99
 CT + TT 22 (10) 63 (10.0)  
COX-1 (rs3842787)
 CC 171 (77.7) 504 (80.0) 0.76
 CT + TT 49 (22.3) 126 (20.0)  
COX-2 (rs689466)
 AA 63 (28.6) 180 (29.6) 0.89
 AG + GG 157 (71.4) 450 (71.4)  
COX-2 (rs20417)
 GG 142 (64.5) 441 (70.0) 0.26
 GC + CC 78 (35.5) 189 (30.0)  
TXAS1 (rs194149)
 GG 75 (34.1) 190 (30.2) 0.42
 AG + AA 145 (65.1) 440 (69.8)  
TXAS1 (rs2267679)
 TT 178 (80.9) 522 (82.9) 0.53
 CC + CT 42 (19.1) 108 (17.1)  
TXAS1 (rs41708)
 GG 136 (61.8) 373 (59.2) 0.72
 TT + GT 84 (38.2) 257 (40.8)  
P2Y1 (rs701265)
 AA 116 (52.7) 341 (54.1) 0.48
 AG + GG 104 (47.3) 289 (45.9)  
P2Y1 (rs1439010)
 AA 114 (51.8) 346 (54.9) 0.32
 AG + GG 106 (48.2) 284 (45.1)  
P2Y1 (rs1371097)
 CC 106 (48.2) 373 (59.2) 0.01
 TT + CT 114 (51.8) 257 (40.8)  
P2Y12 (rs16863323)
 CC 48 (21.8) 158 (25.1) 0.21
 TT + CT 172 (78.2) 472 (74.9)  
P2Y12 (rs9859538)
 GG 154 (70.0) 472 (74.9) 0.16
 AG + AA 66 (30.0) 158 (25.1)  
GPIIIa (rs2317676)
 AA 132 (60.0) 404 (64.1) 0.24
 AG + GG 88 (40.0) 64 (35.9)  
GPIIIa (rs11871251)
 AA 77 (35.0) 190 (30.2) 0.51
 AG + GG 143 (65.0) 440 (69.8)