Table 2 Association of SNPs with responses of aspirin in IS patients (%)
|  | AR + ASR | AS | P-value |
|---|---|---|---|
n = 220 | n = 630 | ||
COX-1 (rs1236913) | |||
 CC | 198 (90.0) | 567 (90.0) | 0.99 |
 CT + TT | 22 (10) | 63 (10.0) |  |
COX-1 (rs3842787) | |||
 CC | 171 (77.7) | 504 (80.0) | 0.76 |
 CT + TT | 49 (22.3) | 126 (20.0) |  |
COX-2 (rs689466) | |||
 AA | 63 (28.6) | 180 (29.6) | 0.89 |
 AG + GG | 157 (71.4) | 450 (71.4) |  |
COX-2 (rs20417) | |||
 GG | 142 (64.5) | 441 (70.0) | 0.26 |
 GC + CC | 78 (35.5) | 189 (30.0) |  |
TXAS1 (rs194149) | |||
 GG | 75 (34.1) | 190 (30.2) | 0.42 |
 AG + AA | 145 (65.1) | 440 (69.8) |  |
TXAS1 (rs2267679) | |||
 TT | 178 (80.9) | 522 (82.9) | 0.53 |
 CC + CT | 42 (19.1) | 108 (17.1) |  |
TXAS1 (rs41708) | |||
 GG | 136 (61.8) | 373 (59.2) | 0.72 |
 TT + GT | 84 (38.2) | 257 (40.8) |  |
P2Y1 (rs701265) | |||
 AA | 116 (52.7) | 341 (54.1) | 0.48 |
 AG + GG | 104 (47.3) | 289 (45.9) |  |
P2Y1 (rs1439010) | |||
 AA | 114 (51.8) | 346 (54.9) | 0.32 |
 AG + GG | 106 (48.2) | 284 (45.1) |  |
P2Y1 (rs1371097) | |||
 CC | 106 (48.2) | 373 (59.2) | 0.01 |
 TT + CT | 114 (51.8) | 257 (40.8) |  |
P2Y12 (rs16863323) | |||
 CC | 48 (21.8) | 158 (25.1) | 0.21 |
 TT + CT | 172 (78.2) | 472 (74.9) |  |
P2Y12 (rs9859538) | |||
 GG | 154 (70.0) | 472 (74.9) | 0.16 |
 AG + AA | 66 (30.0) | 158 (25.1) |  |
GPIIIa (rs2317676) | |||
 AA | 132 (60.0) | 404 (64.1) | 0.24 |
 AG + GG | 88 (40.0) | 64 (35.9) |  |
GPIIIa (rs11871251) | |||
 AA | 77 (35.0) | 190 (30.2) | 0.51 |
 AG + GG | 143 (65.0) | 440 (69.8) |  |