Meta-analysis on the prevalence of REM sleep behavior disorder symptoms in Parkinson’s disease

BMC Neurology

Table 1 Characteristics of studies included in the Meta-analysis

Author	Year	Study design	Country	Population	PD cases	PD + RBD Number	Control Number	Con + RBD Number	RBD assessment	RBD diagnosis	RBD assessment before or after PD diagnosis	NOS score
Wu [14]	2015	case-control	Taiwan	Taiwan National Health Insurance Research Database	705	30	2820	33	ICD-9-CM	definite	before	8
Sunyer [15]	2015	case-control	Spanish and Austrian	outpatient clinics	109	30	107	3	NMS-SQ	probable	after	8
Baig [16]	2015	case-control	UK	Oxford Parkinson Disease Center	796	253	287	42	RBD-SQ	definite	after	8
Trinh [17]	2014	case-control	Tunisia	Institut National de Neurologie, Tunis	390	100	124	10	Questionnaire	probable	after	7
Doring [21]	2014	cross-section	Germany	Paracelsus Elena Klinik in Kassel	158	40	110	2	PSG	definite	after	8
Khoo [18]	2013	case-control	UK	Newcastle-upon-Tyne and Gateshead	159	55	99	8	NMS-SQ	probable	after	8
Adler [19]	2011	case-control	USA	Banner Sun Health Research Institute	49	34	175	23	MSQ	probable	after	8
Chaudhuri [20]	2006	case-control	Multicenter	Multicenter	123	40	96	10	NMS-SQ	probable	after	9
Total					2462	582 (23.6%)	3818	131 (3.4%)

PD Parkinson disease, RBD Rapid eye movement behavior disorder, ICD International classification of disease, NMS non-motor symptom, SQ screening questionnaire, MSQ Mayo Sleep Questionnaire, PSG polysomnography, NOS Newcastle-Ottawa Scale

ISSN: 1471-2377