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Table 1 Characteristics of studies included in the Meta-analysis

From: Meta-analysis on the prevalence of REM sleep behavior disorder symptoms in Parkinson’s disease

Author Year Study design Country Population PD cases PD + RBD Number Control Number Con + RBD Number RBD assessment RBD diagnosis RBD assessment before or after PD diagnosis NOS score
Wu [14] 2015 case-control Taiwan Taiwan National Health Insurance Research Database 705 30 2820 33 ICD-9-CM definite before 8
Sunyer [15] 2015 case-control Spanish and Austrian outpatient clinics 109 30 107 3 NMS-SQ probable after 8
Baig [16] 2015 case-control UK Oxford Parkinson Disease Center 796 253 287 42 RBD-SQ definite after 8
Trinh [17] 2014 case-control Tunisia Institut National de Neurologie, Tunis 390 100 124 10 Questionnaire probable after 7
Doring [21] 2014 cross-section Germany Paracelsus Elena Klinik in Kassel 158 40 110 2 PSG definite after 8
Khoo [18] 2013 case-control UK Newcastle-upon-Tyne and Gateshead 159 55 99 8 NMS-SQ probable after 8
Adler [19] 2011 case-control USA Banner Sun Health Research Institute 49 34 175 23 MSQ probable after 8
Chaudhuri [20] 2006 case-control Multicenter Multicenter 123 40 96 10 NMS-SQ probable after 9
Total      2462 582 (23.6%) 3818 131 (3.4%)     
  1. PD Parkinson disease, RBD Rapid eye movement behavior disorder, ICD International classification of disease, NMS non-motor symptom, SQ screening questionnaire, MSQ Mayo Sleep Questionnaire, PSG polysomnography, NOS Newcastle-Ottawa Scale