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Table 1 Comparison of healthcare exposure of reference cohort (A) and transient ischemic attack (TIA) study cohort before (B) and after (C) index hospitalization

From: Management, prognosis and predictors of unfavourable outcomes in patients newly hospitalized for transient ischemic attack: a real-world investigation from Italy

  Reference cohort TIA study cohort p-value
One year before index hospitalization (A) One year before index hospitalization (B) One year after index discharge (C) (A vs. B) (B vs. C)
Drugs
 Blood pressure-lowering agents 4,544 (58.4%) 5,255 (67.6%) 5,819 (74.8%) <0.0001 <0.0001
 Lipid-lowering agents 1,358 (17.5%) 1,446 (18.6%) 2,651 (34.1%) 0.0612 <0.0001
 Antiplatelet drugs 2,162 (27.8%) 2,754 (35.4%) 5,926 (76.2%) <0.0001 <0.0001
 Oral anticoagulants 421 (5.4%) 499 (6.4%) 997 (12.8%) 0.0077 <0.0001
 Antiarrhythmics 345 (4.4%) 416 (5.3%) 535 (6.9%) 0.0082 <0.0001
 Antidiabetics 867 (11.1%) 1,233 (15.9%) 1,300 (16.7%) 0.0192 0.0002
 None of the previous 2,720 (35.0%) 1,958 (25.2%) 667 (8.6%) <0.0001 <0.0001
Diagnostic procedures
 Cardiac doppler ultrasonography 690 (8.9%) 845 (10.9%) 1,075 (13.8%) <0.0001 <0.0001
 Carotid doppler ultrasonography 633 (8.1%) 759 (9.8%) 1,172 (15.1%) 0.0004 <0.0001
 Neuroimaging or cerebral angiography 156 (2.0%) 277 (3.6%) 769 (9.9%) <0.0001 <0.0001
 Electrocardiogram 1,739 (22.4%) 2,396 (30.8%) 2,525 (32.5%) <0.0001 0.0119
 None of the previous 5,465 (70.3%) 4,744 (61.0%) 3,863 (49.7%) <0.0001 <0.0001
Laboratory tests
 Total cholesterol 3,622 (46.6%) 3,827 (49.2%) 3,698 (47.6%) 0.0007 0.0149
 Glycosylated haemoglobin, Type A1C 1,070 (13.8%) 1,339 (17.2%) 1,434 (18.4%) <0.0001 0.0024
 None of the previous 3,958 (50.9%) 3,720 (47.8%) 3,775 (48.5%) <0.0001 0.1947
 None of the previous drugs, diagnostic procedures, nor laboratory tests 1,652 (21.2%) 1,104 (14.2%) 388 (5.0%) <0.0001 <0.0001