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Table 2 Therapeutic indicator of cognition: ΔMMSE

From: Cilostazol as an add-on therapy for patients with Alzheimer’s disease in Taiwan: a case control study

Therapeutic response, N (%)

Favorablea,21 (31.7)

Poorb,39(68.3)

p-value

Age, years (mean ± SD)

82.3 ± 5.6

82.5 ± 5.6

0.908

Education, years (mean ± SD)

7.5 ± 4.7

8.1 ± 4.8

0.634

Gender, female (%)

15 (71.4)

31 (79.5)

0.482

1st CDR-SB

7.4 ± 3.6

8.4 ± 3.3

0.292

1st MMSE

14.1 ± 7.1

14.6 ± 5.9

0.766

Cilostazol use

  

0.015

No

6 (20.0)

24 (80.0)

 

Yes

15 (50.0)

15 (50.0)

 

ApoE ε4(+),n (%)

7 (35.0)

5 (14.3)

0.074

  1. MMSE Mini-Mental Status Examination, CDR_SB Clinical Dementia Rating Sum of Boxes scale, ApoE apolipoprotein E, ΔMMSE 2nd MMSE – 1st MMSE
  2. aΔMMSE ≥0
  3. bΔMMSE < 0