Skip to main content
Fig. 4 | BMC Neurology

Fig. 4

From: Long noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) inhibits proliferation and invasion of glioma cells by suppressing the Wnt/β-catenin signaling pathway

Fig. 4

LncRNA PTCSC3 overexpression inhibits the migration and invasion of U87 cells. a Wound healing assay was used to determine the migration ability of U87 cells with or without lncRNA PTCSC3 overexpression. Representative images of 0 h and 24 h of three repeated experiments are presented. b Transwell assay was performed to determine the invasion ability of U87 and U251 cells with or without lncRNA PTCSC3 overexpression. The representative images of invasive cells in the lower chamber stained with crystal violet. c The quantification of migration ability of U87 cells were presented as percentage of the wound area. The quantification of U87 (d) and U251 (e) cell invasion is presented as invasive cell numbers per field. qRT-PCR analysis of the mRNA expression levels of MMP1 (f), MMP2 (g), MMP9 (h) and MMP13 (i) in U87 and U251 cells with or without lncRNA PTCSC3 overexpression. Data are expressed as the means ± S.D of three independent experiments. “**” indicates P < 0.01

Back to article page

BMC Neurology

ISSN: 1471-2377

Contact us