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Fig. 6 | BMC Neurology

Fig. 6

From: Long noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) inhibits proliferation and invasion of glioma cells by suppressing the Wnt/β-catenin signaling pathway

Fig. 6

LncRNA PTCSC3 overexpression inhibits the Wnt/β-catenin signaling pathway by suppressing LRP6. qRT-PCR analysis of the mRNA expression levels of FZD8 (a), LRP6 (b), Axin1 (c), C-myc (d) and Cyclin D1 (e) in cells with overexpression or knockdown of lncRNA PTCSC3. f Western blot analysis of LRP6, Axin1, Active catenin, C-myc and Cyclin D1 in U87 cells. GAPDH was used as loading control. Representative images of three repeated experiments are presented. Data are expressed as the means ± S.D of three independent experiments. “*” indicates P < 0.05, “**” indicates P < 0.01

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