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Table 1 Correlation between patients’ consent to be referred to a DBS center, clinical characteristics and the contents of clarification sessions

From: How to improve patient education on deep brain stimulation in Parkinson’s disease: the CARE Monitor study

   Group Consent Group Refusal  
N = 114 (43.2%) N = 150 (56.8%)
N Median 25./75. Quartiles Median 25./75.Quartiles p*
Numerical Data
 Age 262 63 53–70 67 60–71 0.002
 Disease duration 245 9 5–12 8 6–12 0.618
 Hoehn & Yahr Stage 250 3 2–3 3 2–3 0.995
 Eligibility for DBS (STIMULUS Score) 260 8 7–9 8 7–9 0.682
 Subjective Impairment 255 7 6–8 7 6–8 0.178
 Number of topics addressed in the clarification talk 264 6 4–9 5 3–9 ​0.001
Categorial Data N   % N % p*
Gender Male 73 64.0 99 66.0 0.795
Female 41 36.0 51 34.0
Occupation Working 21 18.4 17 11.3 0.362
Retired 79 69.3 118 78.7
Unemployed 13 11.4 14 9.3
Subtype Akinetic-rigid 45 39.5 33 22.0 ​0.008
Tremor dominant 21 18.4 38 25.3
Equivalent 48 42.1 79 52.7
Evaluation of the information material Helpful 79 89.8 77 69.4 <​0.001
Uncertain 8 9.1 20 18.0
Not helpful 1 1.1 14 12.6
Information source Media 4 3.5 9 6.0 0.265
Doctor 93 81.6 117 78.0 0.539
Support group 3 2.6 8 5.3 0.360
Others 1 0.9 1 0.7 >0.999
Patient with DBS 3 2.6 0 0.0 0.079
Contents of clarification talk motor improvement 104 91.2 117 78.0 0.004
quality of life 106 93.0 114 76.0 <​0.001
side effects of medication 86 75.4 76 50.7 <0.001
optimal time frame 66 57.9 50 33.3 <0.001
expectations 60 52.6 62 41.3 0.081
change of role model in partnership 20 17.5 25 16.7 0.870
patients fears 20 17.5 20 13.3 0.388
evidence of DBS 44 38.6 34 22.7 ​0.006
experience with DBS 43 37.7 54 30.0 0.191
complications of DBS surgery 63 55.3 74 49.3 0.385
side effects of DBS 58 50.9 63 42.0 0.171
effects of medication withdrawal 32 28.1 39 26.0 0.780
progression of PD 52 45.6 58 38.7 0.260
others 16 14.0 9 6.0 ​0.034
  1. * To analyze the impact of numerical data on patients’ decisions, Mann-Whitney U tests were calculated and the median and 25.-75. quartiles are presented. For categorial variables with more than two categories (subtype and occupation) Chi-Square tests were conducted. For categorial variables with two categories, Fisher's exact tests were conducted. Exact two-tailed p values are presented. A variable with a p value < 0.05 was considered as a potential predictive variable and therefore included in the binary regression analysis.
  2. ‡ In the categories information source and contents of clarification talk more than one option could be reported. Therefore, Fisher's exact tests were calculated for the prevalence or absence of each topic/source and the resulting p values are presented. To clarify the presentation only the number of prevalent cases are shown.
  3. The entries in italicized represent significant p values (lower than 0.05)