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Table 1 Baseline characteristics of patients

From: Syncope and Epilepsy coexist in ‘possible’ and ‘drug-resistant’ epilepsy (Overlap between Epilepsy and Syncope Study - OESYS)

 

Total population (n = 107)

Possible Epilepsy (n = 63, 58.9%)

Drug- resistant Epilepsy (n = 44, 41.1%)

Mean age, years (mean ± SD, range)

56 ± 21 (18–88)

52 ± 21 (18–88)

62 ± 18 (29–88)

Male gender, n (%)

46 (43.0)

28 (44.4)

18 (40.9)

Heart diseasesa, n (%)

35 (32.7)

13 (20.6)

22 (50.0)

Neurological diseasesb, n (%)

32 (29.9)

22 (34.9)

10 (22.7)

Cardiovascular drugsc, n (%)

46 (43.0)

21 (33.3)

25 (56.8)

Antiepileptic drugsd, n (%)

77 (72.0)

33 (52.4)

44 (100.0)

T-LOC/patient/year (mean ± SD, range)

4 ± 4 (2–20)

3 ± 4 (2–20)

4 ± 4 (2–20)

T-LOC Prodromal symptoms

66 (61.7)

40 (63.5)

26 (59.1)

After T-LOC characteristics

 Involuntary movements

58 (54.2)

37 (58.7)

21 (47.7)

 Mental contusion, n (%)

26 (24.3)

26 (41.3)

12 (27.3)

 Physical injury, n (%)

55 (51.4)

31 (49.2)

24 (54.6)

Comorbidities, n (%)

 Hypertension, n (%)

41 (38.3)

20 (31.7)

21 (47.7)

 Diabetes, n (%)

10 (9.3)

6 (9.5)

4 (9.1)

 Dyslipidemia, n (%)

18 (16.8)

9 (14.3)

9 (20.5)

  1. T-LOC transient loss of consciousness
  2. aIschemic cardiomyopathy, atrial fibrillation, pulmonary embolism, heart failure
  3. bStroke, Parkinson’s disease, dementia, limbic encephalitis, normal pressure hydrocephalus
  4. cDiuretics, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, nitrate, alpha-blockers, beta-blockers, antiarrhythmics, cardiac glycosides
  5. dPhenobarbital, phenytoin, lamotrigine, valproate, levetiracetam, carbamazepine, gabapentin, pregabalin, topiramate, primidone, vigabatrin