Table 4 Grading of Recommendations, Assessment, Development and Evaluation (GRADE) grid for the strength of the recommendation

GRADE strength

Strong

Weak/conditional

Exception

Weak/conditional

Strong

Assessors’ view of the balance of desirable and undesirable consequences of the intervention

Desirable consequences clearly outweigh undesirable consequences

Desirable consequences probably outweigh undesirable consequences

Undesirable consequences probably outweigh desirable consequences

Undesirable consequences clearly outweigh desirable consequences

Recommendation

We recommend to “do something”

We suggest/conditionally recommend to “do something”

We suggest/conditionally recommend to “not do something”

We recommend to “not do something”