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Table 3 Relapse characteristics according to discontinuation status at 1, 2 and 3 years

From: Reasons for discontinuation of subcutaneous interferon β-1a three times a week among patients with multiple sclerosis: a real-world cohort study

 

sc IFN β-1a tiw

 

Follow-up at 1 year

Follow-up at 2 years

Follow-up at 3 years

 

Continued

Discontinued

Continued

Discontinued

Continued

Discontinued

Total patients, n (%)

2505 (63.0)

1470 (37.0)

1310 (50.5)

1282 (49.5)

736 (44.2)

928 (55.8)

Relapses per year, mean (SD)

0.18 (0.52)

0.32 (0.67)

0.14 (0.34)

0.26 (0.49)

0.12 (0.26)

0.23 (0.42)

Patients with high relapses, n (%)a

97 (3.9)

84 (5.7)

46 (3.5)

73 (5.7)

21 (2.9)

52 (5.6)

  1. IFN, interferon, sc subcutaneous, SD standard deviation, tiw three times a week
  2. aHigh relapse activity defined as having ≥2 relapses in the first year prior to start of subcutaneous interferon β-1a, three times weekly