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Table 6 Patient Global Impression of Change (PGIC) responses

From: Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study

Response Patients, n (%)
  First treatment Second treatment Third treatment
Week 2 n = 408   
 Improved 258 (63.2)   
 No change 117 (28.7)   
 Worsened 33 (8.1)   
Week 8 n = 368   
 Improved 231 (62.8)   
 No change 110 (29.9)   
 Worsened 27 (7.3)   
Week 12 n = 367 n = 150 n = 47
 Improved 224 (61.0) 112 (74.7) 37 (78.7)
 No change 116 (31.6) 30 (20.0) 8 (17.0)
 Worsened 27 (7.4) 8 (5.3) 2 (4.3)
Week 26 n = 207 n = 101 n = 28
 Improved 113 (54.6) 67 (66.3) 23 (82.1)
 No change 76 (36.7) 26 (25.7) 3 (10.7)
 Worsened 18 (8.7) 8 (7.9) 2 (7.1)
Week 39 n = 177 n = 81 n = 21
 Improved 96 (54.2) 50 (61.7) 18 (85.7)
 No change 65 (36.7) 24 (29.6) 1 (4.8)
 Worsened 16 (9.0) 7 (8.6) 2 (9.5)
Week 52 n = 176 n = 56 n = 7
 Improved 93 (52.8) 38 (67.9) 5 (71.4)
 No change 71 (40.3) 14 (25.0) 1 (14.3)
 Worsened 12 (6.8) 4 (7.1) 1 (14.3)
  1. Improved: slightly, much, very much; Worsened: slightly, much, very much