Table 1 Baseline demographics and epilepsy characteristics in the 1-year pre-index period
Characteristic | Overall population | Matched population | ||||
|---|---|---|---|---|---|---|
EIAED (n = 2752) | nEAAED (n = 2137) | p valuea | EIAED (n = 951) | nEAAED (n = 951) | p valuea | |
Age, mean (SD), years | 54.2 (19.8) | 45.9 (19.9) | <0.0001 | 47.7 (19.9) | 48.0 (20.0) | 0.7969 |
Age group, n (%) | <0.0001 | 1.0000 | ||||
16–20 | 116 (4.2) | 239 (11.2) | 75 (7.9) | 75 (7.9) | ||
21–30 | 261 (9.5) | 349 (16.3) | 144 (15.1) | 144 (15.1) | ||
31–40 | 404 (14.7) | 344 (16.1) | 167 (17.6) | 167 (17.6) | ||
41–50 | 434 (15.8) | 380 (17.8) | 160 (16.8) | 160 (16.8) | ||
51–60 | 406 (14.8) | 285 (13.3) | 133 (14.0) | 133 (14.0) | ||
61–70 | 425 (15.4) | 236 (11.0) | 119 (12.5) | 119 (12.5) | ||
71–80 | 434 (15.8) | 191 (8.9) | 94 (9.9) | 94 (9.9) | ||
81–90 | 237 (8.6) | 96 (4.5) | 47 (4.9) | 47 (4.9) | ||
Over 90 | 35 (1.3) | 17 (0.8) | 12 (1.3) | 12 (1.3) | ||
Gender, n (%) | <0.0001 | 0.7130 | ||||
Female | 1243 (45.2) | 1339 (62.7) | 506 (53.2) | 514 (54.0) | ||
Male | 1509 (54.8) | 798 (37.3) | 445 (46.8) | 437 (46.0) | ||
Germaine-Smith epilepsy-specific comorbidity index, mean score (SD) | 1.0 (2.0) | 0.6 (1.6) | <0.0001 | 0.7 (1.6) | 0.7 (1.5) | 0.8272 |
Time since first epilepsy diagnosis, years | ||||||
Mean (SD) | 4.5 (10.3) | 8.5 (13.5) | <0.0001 | 5.8 (11.1) | 6.2 (12.0) | 0.4604 |
Median (P25–P75) | 0.2 (0.1–2.5) | 1.3 (0.1–10.9) | 0.4 (0.1–5.8) | 0.6 (0.1–6.3) | ||
Epilepsy type, n (%) | 0.0011 | 0.7202 | ||||
Generalized | 301 (10.9) | 212 (9.9) | 78 (8.2) | 85 (8.9) | ||
Partial | 470 (17.1) | 291 (13.6) | 148 (15.6) | 138 (14.5) | ||
Unspecified | 1981 (72.0) | 1634 (76.5) | 725 (76.2) | 728 (76.6) | ||