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Fig. 5 | BMC Neurology

Fig. 5

From: Concordance analysis of microarray studies identifies representative gene expression changes in Parkinson’s disease: a comparison of 33 human and animal studies

Fig. 5

Principal component analysis of differential gene expression in Parkinson’s disease, Alzheimer’s disease and brain tumor studies. The tumor studies are mostly distant in principal component space from PD or AD studies, suggesting different patterns of gene expression in the two diseases; whilst the AD studies look very similar to those of Parkinson’s disease, suggesting that gene expression patterns in these neurodegenerative diseases could be related to some extent. This is most clearly visualised in the second and third principal components; a similar separation is seen in the first two principal components (see Additional file 13)

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