Table 2 Genes highly differentially expressed in multiple Parkinson’s disease studies. Table shows the number of times a gene is in the top 50 genes by absolute log-fold change in each study
Gene | All studies | Human studies | Studies of the SN |
|---|---|---|---|
Up-regulated | |||
HSPA1A | 4 | 3 | 3 |
RELN | 4 | 4 | 3 |
PTPRC | 3 | 2 | 0 |
LCN2 | 3 | 0 | 0 |
PLIN4 | 3 | 0 | 0 |
MAFF | 3 | 2 | 2 |
SLCO4A1 | 3 | 3 | 2 |
HSPA1B | 3 | 3 | 3 |
IGF2BP2 | 3 | 0 | 0 |
CDKN1A | 3 | 0 | 0 |
ENC1 | 3 | 2 | 1 |
Down-regulated | |||
EGR2 | 6 | 0 | 0 |
FOS | 5 | 2 | 1 |
RGS4 | 5 | 5 | 3 |
TAC1 | 5 | 4 | 3 |
SLC6A3 | 4 | 3 | 3 |
AGTR1 | 4 | 4 | 3 |
FGF13 | 4 | 3 | 4 |
PCSK1 | 4 | 3 | 2 |
NPTX2 | 4 | 1 | 1 |
GABBR2 | 4 | 3 | 2 |
NR4A2 | 4 | 3 | 4 |
EIF1AY | 3 | 2 | 2 |
SATB2 | 3 | 0 | 0 |
RET | 3 | 1 | 2 |
SNCA | 3 | 3 | 0 |
TTR | 3 | 0 | 0 |
CCK | 3 | 0 | 0 |
DDC | 3 | 3 | 3 |
SLC18A2 | 3 | 3 | 3 |
ALDH1A1 | 3 | 3 | 3 |
KCNJ6 | 3 | 2 | 2 |
TMEM255A | 3 | 3 | 3 |
SCG2 | 3 | 3 | 3 |
GPR26 | 3 | 2 | 3 |
DCLK1 | 3 | 2 | 0 |
DUSP1 | 3 | 2 | 1 |
HPCAL4 | 3 | 2 | 1 |
SYNGR3 | 3 | 3 | 2 |
PREPL | 3 | 3 | 0 |
STMN2 | 3 | 3 | 2 |
VSNL1 | 3 | 3 | 2 |
NTS | 3 | 2 | 3 |