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Table 1 Comparison of disease progression for Patient A and Patient B

From: Conjugal amyotrophic lateral sclerosis: a case report from Scotland

 

Patient A

Patient B

0 months

Onset of symptoms

 

6 months

Presentation to neurology clinic

 

10 months

Diagnosis of ALS

 

15 months

Progression of arm symptoms

 
 

Bilateral leg weakness

 

18 months

Bilateral flail arms

Onset of symptoms

 

Postural dyspnoea

 

22 months

Commenced nocturnal non-invasive ventilation (NIV)

 

25 months

Commenced daytime NIV

Presentation to neurology clinic

 

Swallowing difficulties

 
 

Unable to walk

 

26 months

Insertion of radiological inserted gastrostomy tube

Diagnosis of ALS

30 months

 

Progression of symptoms

  

Unable to dress or eat independently

53 months

 

Insertion of percutaneous endoscopic gastrostomy tube

59 months

Commenced 24-hr NIV

Commenced on intermittent NIV

  

Bilateral flail arms

  

Unable to walk more than a few steps

61 months

Death

 

62 months

 

Death