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Table 2 Bone markers and PTH throughot the study period

From: High dose vitamin D supplementation does not affect biochemical bone markers in multiple sclerosis – a randomized controlled trial

 

CTX1 (μg/l)

PINP (μg/l)

PTH pmol/L

Placebo

Vitamin D

p-value*

Placebo

Vitamin D

p-value*

Placebo

Vitamin D

p-value*

Baseline. mean (SD)

0.20 (0.10)

0.22 (0.11)

0.59

43.10 (15.1)

40.32 (10.0)

0.57

4.75 (1.08)

4.68 (1.29)

0.66

Week 48. mean (SD)

0.22 (0.16)

0.21 (0.11)

0.79

43.36 (17.2)

38.56 (10.6)

0.43

3.68 (1.04)

3.13 (0.96)

0.017

Week 96. mean (SD)

0.23 (0.17)

0.23 (0.12)

0.98

42.54 (15.0)

43.52 (10.6)

0.22

3.96 (1.27)

3.39 (1.00)

0.046

  1. *Obtained from linear mixed model