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Table 4 Effect of high dose vitamin D supplementation compared to placebo on bone markers

From: High dose vitamin D supplementation does not affect biochemical bone markers in multiple sclerosis – a randomized controlled trial

  Week 48 Week 96
Change from baseline, percent difference (95% CI) p-value* Change from baseline, percent difference (95%CI) p-value*
PINP -5.10% (−17.77, 7.56) 0.43 10.26% (−2.48 22.99) 0.12
CTX1 -6.68% (−33.62, 20.25) 0.63 −3.60% (−30.67, 23.48) 0.80
PTH -13.69% (−29.55, 2.12) 0.09 −10.9% (−26.81, 5.03) 0.17
  1. *Obtained from linear mixed model