Fig. 2
Frequencies of peripheral myelin antigen-specific T cell responses in typical versus atypical CIDP patients. Typical (n = 8) vs atypical CIDP patients (n = 12) vs. HC (n = 14) were measured by IFN-y ELISPOT. Background corrected SFU per 106 PBMC. Significantly, elevated SFU were observed in atypical CIDP patients vs. HC for PMP-22 32-51, PMP-22 51-64, PMP-22 120-133, P2 14-25, P0 180-199, MBP 82-100. (*p < 0.05, **p < 0.01, ***p < 0.001). Scatter dot plot with line at mean. For P0 180-199, a cut-off value of 5 SFU/106 PBMC in T cell-Elispot having a sensitivity of 91,7% (11/12) and a specificity of 62,5% (5/8) with AUC 0.69. For MBP 82-100 using a cut-off value of 10 SFU per 106 PBMC in a T cell-Elispot assay had a sensitivity of 75,0% (9/12) and a specificity of 62,5% (5/8) with AUC 0.68