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Table 3 Comparison before and after propensity score matchinga in patients with diabetes and acute ischemic stroke admitted within 72 h

From: Association of fibrinogen level with early neurological deterioration among acute ischemic stroke patients with diabetes

 

Before matching

After matching

 

END (n = 262)

Non-END (n = 1098)

P

END (n = 261)

Non-END (n = 522)

P

Age

65.3 ± 11.8

65.1 ± 11.7

0.771

65.3 ± 11.8

64.8 ± 11.8

0.593

Male sex

160 (61.1%)

700 (63.8%)

0.418

159 (60.9%)

315 (60.3%)

0.877

Hypertension

213 (81.6%)

812(74.6%)

0.017

213 (81.6%)

431 (82.6%)

0.741

Initial NIHSS

8.0 ± 6.6

5.7 ± 6.4

<0.001

7.9 ± 6.6

7.6 ± 6.8

0.562

Discharge NIHSS

10.4 ± 10.6

3.6 ± 5.7

<0.001

10.4 ± 10.5

4.8 ± 6.5

<0.001

TOAST

  

0.167

76 (23.4%)

 

0.169

 Cardioembolism

52 (19.8%)

221 (20.1%)

 

52 (19.9%)

111 (21.3%)

 

 Atherosclerosis

88 (33.6%)

328 (29.8%)

 

88 (33.7%)

163 (31.2%)

 

 Small artery disease

64 (24.4%)

235 (21.4%)

 

64 (24.5%)

102 (19.5%)

 

 Others

58 (22.1%)

314 (28.6%)

 

57 (21.8%)

146 (28.0%)

 

Fasting glucose (mg/dL)

190.9 ± 84.1

184.0 ± 85.5

0.238

190.7 ± 84.2

189.5 ± 87.8

0.852

Glycated hemoglobin (%)

7.5 ± 1.7

7.3 ± 1.5

0.119

7.5 ± 1.7

7.4 ± 1.6

0.392

Urine protein positivity

59 (35.1%)

143 (21.2%)

<0.001

58 (34.7%)

76 (23.4%)

0.007

Fibrinogen (mg/dL)

392.9 ± 204.2

359.0 ± 119.1

0.012

392.8 ± 204.6

361.1 ± 123.1

0.009

ESR (mm)

22.0 ± 20.5

21.2 ± 20.1

0.547

22.0 ± 20.5

21.3 ± 18.9

0.643

CRP (mg/dL)

0.9 ± 2.3

0.9 ± 2.8

0.931

0.9 ± 2.3

1.1 ± 3.2

0.528

BMI

   

24.2 ± 3.3

24.5 ± 3.2

0.317

Metabolic syndrome

149 (56.9%)

609 (55.5%)

0.681

149 (57.1%)

305 (58.4%)

0.720

Lipid panel

      

 T.chol (mg/dL)

179.6 ± 43.2

181.7 ± 69.0

0.629

179.3 ± 43.0

182.2 ± 47.4

0.396

 LDL (mg/dL)

106.3 ± 37.7

106.1 ± 37.4

0.919

106.0 ± 37.4

107.5 ± 38.1

0.604

 HDL (mg/dL)

43.7 ± 11.7

43.9 ± 15.0

0.825

43.7 ± 11.7

44.0 ± 12.1

0.775

 TG (mg/dL)

158.6 ± 113.5

163.4 ± 133.4

0.600

158.7 ± 113.7

165.6 ± 153.3

0.521

  1. END early neurological deterioration, NIHSS National Institutes of Health Stroke Scale, TOAST trial of Org 10,172 in acute stroke treatment, ESR erythrocyte sedimentation rate, CRP c-reactive protein, BMI body mass index, T.chol total cholesterol, LDL low density lipoprotein, HDL high density lipoprotein, TG triglyceride
  2. a Age, sex, initial NIHSS and TOAST were adjusted