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Table 1 Baseline characteristics of the 31 patients

From: Association between total-Tau and brain atrophy one year after first-ever stroke

Demographics

Baseline

Follow-up

Male, n

19 (61%)

 

Mean age + −SD, years 70.2 (SD 11.7)

  < 9 years of education

5 (16%)

 

Stroke subtype

 Cerebral infarction

29 (94%)

 

 TIA

2 (6%)

 

Risk factors, n

 Hypertension

20 (65%)

 

 Hyperlipideamia

23 (74%)

 

 Diabetes

6 (19%)

 

 Current smoking

7 (23%)

 

 Atrial fibrillation

3 (10%)

 

 BMI

18 (58%)

 

TOAST classification, n

 Large-vessel disease

2 (7%)

 

 Cardio-embolic disease

2 (6%)

 

 Small vessel disease

17 (55%)

 

 Stroke of undetermined aetiology

10 (32%)

 

OCSP classification, n

 TACI

0

 

 PACI

13 (42%)

 

 LACI

15 (48%)

 

 POCI

3 (10%)

 

Assessments

 NIHSS, day 1, mean (IQR)

3.06 (1.0-4.0)

0.58 (0.0-1.0)

 BI, mean(IQR)

18.5 (19.5-20.0)

19.48 (20.0-20.0)

 mRS, mean (IQR)

1.35 (0.0-3.0)

1.06 (1.0-1.0)

 Total TAU, mean (IQR)

 

363 (227–382)

 Apoɛ4

9 (29%)

 

 TMT A (seconds) (SD)

86.0 (±97.0)

61.6 (±48.4)

 MMSE (points) (SD)

26.0 (±3.8)

26.7 (±3.9)

 10 word test (words)

20.1 (±6.8)

24.5 (±6.1)

 Ventricular volume (mm^3)(SD)

60,796 (±17,339)

60,334 (±25,118)

 Global brain volume(mm^3) (SD)

1,404,660 (±63,160)

1,368,194 (±142,856)

  1. TIA = Transient Ischemic Attack; Hyperlipidemia = total cholesterol >5 mmol/l or LDL-cholesterol >3 mmol/l; LDL = Low Density Lipoprotein; BMI = body mass index; TOAST = The Trial of Org 10,172 in Acute Stroke Treatment classification; OCSP = Oxfordshire Community Stroke Project classification; TACI = Total Anterior Circulation Infarction; PACI = Partial Anterior Circulation Infarction; LACI = Lacunar Circulation Infarction; POCI = Posterior Circulation Infarction; NIHSS = National Institute of Health Stroke Scale; IQR = Interquartile range; BI = Barthel Activities of Daily Living Index; mRs = modified Rankin scale; Apoɛ4 = apo lipoprotein E allel 4; TMT A = trail making test A; SD = standard deviation); MMSE = mini metal test examination