TY - JOUR AU - Wingerchuk, D. M. AU - Banwell, B. AU - Bennett, J. L. AU - Cabre, P. AU - Carroll, W. AU - Chitnis, T. AU - Seze, J. AU - Fujihara, K. AU - Greenberg, B. AU - Jacob, A. PY - 2015 DA - 2015// TI - International consensus diagnostic criteria for neuromyelitis optica spectrum disorders JO - Neurology VL - 85 UR - https://doi.org/10.1212/WNL.0000000000001729 DO - 10.1212/WNL.0000000000001729 ID - Wingerchuk2015 ER - TY - JOUR AU - Sellner, J. AU - Boggild, M. AU - Clanet, M. AU - Hintzen, R. Q. AU - Illes, Z. AU - Montalban, X. AU - Pasquier, R. A. AU - Polman, C. H. AU - Sorensen, P. S. AU - Hemmer, B. PY - 2010 DA - 2010// TI - EFNS guidelines on diagnosis and management of neuromyelitis optica JO - Eur J Neurol VL - 17 UR - https://doi.org/10.1111/j.1468-1331.2010.03066.x DO - 10.1111/j.1468-1331.2010.03066.x ID - Sellner2010 ER - TY - JOUR AU - Elsone, L. AU - Kitley, J. AU - Luppe, S. AU - Lythgoe, D. AU - Mutch, K. AU - Jacob, S. AU - Brown, R. AU - Moss, K. AU - McNeillis, B. AU - Goh, Y. Y. PY - 2014 DA - 2014// TI - Long-term efficacy, tolerability and retention rate of azathioprine in 103 aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder patients: a multicentre retrospective observational study from the UK JO - Mult Scler VL - 20 UR - https://doi.org/10.1177/1352458514525870 DO - 10.1177/1352458514525870 ID - Elsone2014 ER - TY - JOUR AU - Mandler, R. N. AU - Ahmed, W. AU - Dencoff, J. E. PY - 1998 DA - 1998// TI - Devic's neuromyelitis optica: a prospective study of seven patients treated with prednisone and azathioprine JO - Neurology VL - 51 UR - https://doi.org/10.1212/WNL.51.4.1219 DO - 10.1212/WNL.51.4.1219 ID - Mandler1998 ER - TY - JOUR AU - Costanzi, C. AU - Matiello, M. AU - Lucchinetti, C. F. AU - Weinshenker, B. G. AU - Pittock, S. J. AU - Mandrekar, J. AU - Thapa, P. AU - McKeon, A. PY - 2011 DA - 2011// TI - Azathioprine: tolerability, efficacy, and predictors of benefit in neuromyelitis optica JO - Neurology VL - 77 UR - https://doi.org/10.1212/WNL.0b013e31822a2780 DO - 10.1212/WNL.0b013e31822a2780 ID - Costanzi2011 ER - TY - JOUR AU - Qiu, W. AU - Kermode, A. G. AU - Li, R. AU - Dai, Y. AU - Wang, Y. AU - Wang, J. AU - Zhong, X. AU - Li, C. AU - Lu, Z. AU - Hu, X. PY - 2015 DA - 2015// TI - Azathioprine plus corticosteroid treatment in Chinese patients with neuromyelitis optica JO - J Clin Neurosci VL - 22 UR - https://doi.org/10.1016/j.jocn.2015.01.028 DO - 10.1016/j.jocn.2015.01.028 ID - Qiu2015 ER - TY - JOUR AU - Amin, J. AU - Huang, B. AU - Yoon, J. AU - Shih, D. Q. PY - 2015 DA - 2015// TI - Update 2014: advances to optimize 6-mercaptopurine and azathioprine to reduce toxicity and improve efficacy in the management of IBD JO - Inflamm Bowel Dis VL - 21 UR - https://doi.org/10.1097/MIB.0000000000000197 DO - 10.1097/MIB.0000000000000197 ID - Amin2015 ER - TY - JOUR AU - Cara, C. J. AU - Pena, A. S. AU - Sans, M. AU - Rodrigo, L. AU - Guerrero-Esteo, M. AU - Hinojosa, J. AU - Garcia-Paredes, J. AU - Guijarro, L. G. PY - 2004 DA - 2004// TI - Reviewing the mechanism of action of thiopurine drugs: towards a new paradigm in clinical practice JO - Med Sci Monit VL - 10 ID - Cara2004 ER - TY - JOUR AU - Sahasranaman, S. AU - Howard, D. AU - Roy, S. PY - 2008 DA - 2008// TI - Clinical pharmacology and pharmacogenetics of thiopurines JO - Eur J Clin Pharmacol VL - 64 UR - https://doi.org/10.1007/s00228-008-0478-6 DO - 10.1007/s00228-008-0478-6 ID - Sahasranaman2008 ER - TY - JOUR AU - Fung, C. AU - Vaughn, D. J. AU - Mitra, N. AU - Ciosek, S. L. AU - Vardhanabhuti, S. AU - Nathanson, K. L. AU - Kanetsky, P. A. PY - 2012 DA - 2012// TI - Chemotherapy refractory testicular germ cell tumor is associated with a variant in armadillo repeat gene deleted in Velco-cardio-facial syndrome (ARVCF) JO - Front Endocrinol (Lausanne) VL - 3 ID - Fung2012 ER - TY - JOUR AU - Fairchild, C. R. AU - Maybaum, J. AU - Kennedy, K. A. PY - 1986 DA - 1986// TI - Concurrent unilateral chromatid damage and DNA strand breakage in response to 6-thioguanine treatment JO - Biochem Pharmacol VL - 35 UR - https://doi.org/10.1016/0006-2952(86)90623-4 DO - 10.1016/0006-2952(86)90623-4 ID - Fairchild1986 ER - TY - JOUR AU - Tiede, I. AU - Fritz, G. AU - Strand, S. AU - Poppe, D. AU - Dvorsky, R. AU - Strand, D. AU - Lehr, H. A. AU - Wirtz, S. AU - Becker, C. AU - Atreya, R. PY - 2003 DA - 2003// TI - CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes JO - J Clin Invest VL - 111 UR - https://doi.org/10.1172/JCI16432 DO - 10.1172/JCI16432 ID - Tiede2003 ER - TY - JOUR AU - Burnett, H. F. AU - Tanoshima, R. AU - Chandranipapongse, W. AU - Madadi, P. AU - Ito, S. AU - Ungar, W. J. PY - 2014 DA - 2014// TI - Testing for thiopurine methyltransferase status for safe and effective thiopurine administration: a systematic review of clinical guidance documents JO - Pharmacogenomics J VL - 14 UR - https://doi.org/10.1038/tpj.2014.47 DO - 10.1038/tpj.2014.47 ID - Burnett2014 ER - TY - JOUR AU - Salavaggione, O. E. AU - Wang, L. AU - Wiepert, M. AU - Yee, V. C. AU - Weinshilboum, R. M. PY - 2005 DA - 2005// TI - Thiopurine S-methyltransferase pharmacogenetics: variant allele functional and comparative genomics JO - Pharmacogenet Genomics VL - 15 UR - https://doi.org/10.1097/01.fpc.0000174788.69991.6b DO - 10.1097/01.fpc.0000174788.69991.6b ID - Salavaggione2005 ER - TY - JOUR AU - Collie-Duguid, E. S. AU - Pritchard, S. C. AU - Powrie, R. H. AU - Sludden, J. AU - Collier, D. A. AU - Li, T. AU - McLeod, H. L. PY - 1999 DA - 1999// TI - The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations JO - Pharmacogenetics VL - 9 UR - https://doi.org/10.1097/00008571-199902000-00006 DO - 10.1097/00008571-199902000-00006 ID - Collie-Duguid1999 ER - TY - JOUR AU - Umamaheswaran, G. AU - Kumar, D. K. AU - Adithan, C. PY - 2014 DA - 2014// TI - Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective JO - Indian J Med Res VL - 139 ID - Umamaheswaran2014 ER - TY - JOUR AU - Gray, J. H. AU - Owen, R. P. AU - Giacomini, K. M. PY - 2004 DA - 2004// TI - The concentrative nucleoside transporter family, SLC28 JO - Pflugers Arch VL - 447 UR - https://doi.org/10.1007/s00424-003-1107-y DO - 10.1007/s00424-003-1107-y ID - Gray2004 ER - TY - JOUR AU - Errasti-Murugarren, E. AU - Molina-Arcas, M. AU - Casado, F. J. AU - Pastor-Anglada, M. PY - 2009 DA - 2009// TI - A splice variant of the SLC28A3 gene encodes a novel human concentrative nucleoside transporter-3 (hCNT3) protein localized in the endoplasmic reticulum JO - FASEB J VL - 23 UR - https://doi.org/10.1096/fj.08-113902 DO - 10.1096/fj.08-113902 ID - Errasti-Murugarren2009 ER - TY - JOUR AU - Badagnani, I. AU - Chan, W. AU - Castro, R. A. AU - Brett, C. M. AU - Huang, C. C. AU - Stryke, D. AU - Kawamoto, M. AU - Johns, S. J. AU - Ferrin, T. E. AU - Carlson, E. J. PY - 2005 DA - 2005// TI - Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3) JO - Pharmacogenomics J VL - 5 UR - https://doi.org/10.1038/sj.tpj.6500303 DO - 10.1038/sj.tpj.6500303 ID - Badagnani2005 ER - TY - JOUR AU - Fotoohi, A. K. AU - Lindqvist, M. AU - Peterson, C. AU - Albertioni, F. PY - 2006 DA - 2006// TI - Involvement of the concentrative nucleoside transporter 3 and equilibrative nucleoside transporter 2 in the resistance of T-lymphoblastic cell lines to thiopurines JO - Biochem Biophys Res Commun VL - 343 UR - https://doi.org/10.1016/j.bbrc.2006.02.134 DO - 10.1016/j.bbrc.2006.02.134 ID - Fotoohi2006 ER - TY - STD TI - Mei S, Li X, Gong X, Li X, Yang L, Zhou H, Liu Y, Zhou A, Zhu L, Zhang X et al. LC-MS/MS analysis of erythrocyte thiopurine nucleotides and their association with genetic variants in patients with neuromyelitis optica spectrum disorders taking azathioprine. Ther Drug Monit 2016; doi: 10.1097/FTD.0000000000000362. ID - ref21 ER - TY - JOUR AU - Ketelslegers, I. A. AU - Modderman, P. W. AU - Vennegoor, A. AU - Killestein, J. AU - Hamann, D. AU - Hintzen, R. Q. PY - 2011 DA - 2011// TI - Antibodies against aquaporin-4 in neuromyelitis optica: distinction between recurrent and monophasic patients JO - Mult Scler VL - 17 UR - https://doi.org/10.1177/1352458511412995 DO - 10.1177/1352458511412995 ID - Ketelslegers2011 ER - TY - JOUR AU - Rae, W. AU - Burke, G. AU - Pinto, A. PY - 2016 DA - 2016// TI - A study of the utility of azathioprine metabolite testing in myasthenia gravis JO - J Neuroimmunol VL - 293 UR - https://doi.org/10.1016/j.jneuroim.2016.02.015 DO - 10.1016/j.jneuroim.2016.02.015 ID - Rae2016 ER - TY - JOUR AU - Watanabe, S. AU - Misu, T. AU - Miyazawa, I. AU - Nakashima, I. AU - Shiga, Y. AU - Fujihara, K. AU - Itoyama, Y. PY - 2007 DA - 2007// TI - Low-dose corticosteroids reduce relapses in neuromyelitis optica: a retrospective analysis JO - Mult Scler VL - 13 UR - https://doi.org/10.1177/1352458507077189 DO - 10.1177/1352458507077189 ID - Watanabe2007 ER - TY - JOUR AU - Swann, P. F. AU - Waters, T. R. AU - Moulton, D. C. AU - Xu, Y. Z. AU - Zheng, Q. AU - Edwards, M. AU - Mace, R. PY - 1996 DA - 1996// TI - Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine JO - Science (New York, NY) VL - 273 UR - https://doi.org/10.1126/science.273.5278.1109 DO - 10.1126/science.273.5278.1109 ID - Swann1996 ER - TY - JOUR AU - Elion, G. B. PY - 1989 DA - 1989// TI - The purine path to chemotherapy JO - Science (New York, NY) VL - 244 UR - https://doi.org/10.1126/science.2649979 DO - 10.1126/science.2649979 ID - Elion1989 ER - TY - JOUR AU - Jasiak-Zatonska, M. AU - Kalinowska-Lyszczarz, A. AU - Michalak, S. AU - Kozubski, W. PY - 2016 DA - 2016// TI - The immunology of Neuromyelitis Optica-current knowledge, clinical implications, controversies and future perspectives JO - Int J Mol Sci VL - 17 UR - https://doi.org/10.3390/ijms17030273 DO - 10.3390/ijms17030273 ID - Jasiak-Zatonska2016 ER - TY - JOUR AU - Lu, H. F. AU - Shih, M. C. AU - Chang, Y. S. AU - Chang, J. Y. AU - Ko, Y. C. AU - Chang, S. J. AU - Chang, J. G. PY - 2006 DA - 2006// TI - Molecular analysis of thiopurine S-methyltransferase alleles in Taiwan aborigines and Taiwanese JO - J Clin Pharm Ther VL - 31 UR - https://doi.org/10.1111/j.1365-2710.2006.00707.x DO - 10.1111/j.1365-2710.2006.00707.x ID - Lu2006 ER - TY - JOUR AU - Umamaheswaran, G. AU - Krishna Kumar, D. AU - Kayathiri, D. AU - Rajan, S. AU - Shewade, D. G. AU - Dkhar, S. A. AU - Manjunath, S. AU - Ushakiran, P. AU - Reneega, G. AU - Ritushree, K. PY - 2012 DA - 2012// TI - Inter and intra-ethnic differences in the distribution of the molecular variants of TPMT, UGT1A1 and MDR1 genes in the south Indian population JO - Mol Biol Rep VL - 39 UR - https://doi.org/10.1007/s11033-012-1456-8 DO - 10.1007/s11033-012-1456-8 ID - Umamaheswaran2012 ER - TY - JOUR AU - Lowry, P. W. AU - Franklin, C. L. AU - Weaver, A. L. AU - Pike, M. G. AU - Mays, D. C. AU - Tremaine, W. J. AU - Lipsky, J. J. AU - Sandborn, W. J. PY - 2001 DA - 2001// TI - Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease JO - Gut VL - 49 UR - https://doi.org/10.1136/gut.49.5.665 DO - 10.1136/gut.49.5.665 ID - Lowry2001 ER - TY - JOUR AU - Fernandez-Calotti, P. X. AU - Colomer, D. AU - Pastor-Anglada, M. PY - 2011 DA - 2011// TI - Translocation of nucleoside analogs across the plasma membrane in hematologic malignancies JO - Nucleosides Nucleotides Nucleic Acids VL - 30 UR - https://doi.org/10.1080/15257770.2011.597372 DO - 10.1080/15257770.2011.597372 ID - Fernandez-Calotti2011 ER - TY - JOUR AU - Molina-Arcas, M. AU - Marce, S. AU - Villamor, N. AU - Huber-Ruano, I. AU - Casado, F. J. AU - Bellosillo, B. AU - Montserrat, E. AU - Gil, J. AU - Colomer, D. AU - Pastor-Anglada, M. PY - 2005 DA - 2005// TI - Equilibrative nucleoside transporter-2 (hENT2) protein expression correlates with ex vivo sensitivity to fludarabine in chronic lymphocytic leukemia (CLL) cells JO - Leukemia VL - 19 ID - Molina-Arcas2005 ER - TY - JOUR AU - Minuesa, G. AU - Purcet, S. AU - Erkizia, I. AU - Molina-Arcas, M. AU - Bofill, M. AU - Izquierdo-Useros, N. AU - Casado, F. J. AU - Clotet, B. AU - Pastor-Anglada, M. AU - Martinez-Picado, J. PY - 2008 DA - 2008// TI - Expression and functionality of anti-human immunodeficiency virus and anticancer drug uptake transporters in immune cells JO - J Pharmacol Exp Ther VL - 324 UR - https://doi.org/10.1124/jpet.107.131482 DO - 10.1124/jpet.107.131482 ID - Minuesa2008 ER -