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Table 2 Cognitive status and Neuropsychiatric Inventory among dementia patients

From: Comparison of neuropsychiatric symptoms and diffusion tensor imaging correlates among patients with subcortical ischemic vascular disease and Alzheimer’s disease

 

SIVD

AD

All (n = 24)

CDR = 0.5 (n = 14)

CDR =1 ~ 2 (n = 10)

All (n = 32)

CDR = 0.5 (n = 21)

CDR = 1 ~ 2 (n = 11)

MMSE£££ ǂ $$$

19.08 ± 5.04

21.07 ± 4.34

16.30 ± 4.79

21.03 ± 4.67

22.90 ± 3.75

17.45 ± 4.25

CASI£££ ǂ $$$

61.04 ± 14.78

67.21 ± 13.16

52.40 ± 12.87

67.19 ± 15.20

73.29 ± 13.12

55.55 ± 12.04

Total score

6.42 ± 5.72

5.71 ± 6.33

7.40 ± 4.88

6.88 ± 8.87

5.19 ± 5.39

10.09 ± 12.98

Hyperactivity

0.51 ± 0.82

0.48 ± 0.94

0.55 ± 0.67

0.45 ± 0.89

0.18 ± 0.29

0.98 ± 1.35

 Agitation

0.50 ± 1.45

0.64 ± 1.74

0.30 ± 0.95

0.38 ± 1.19

0.00 ± 0.00

1.09 ± 1.87

 Disinhibition

0.00 ± 0.00

0.00 ± 0.00

0.00 ± 0.00

0.19 ± 1.06

0.00 ± 0.00

0.55 ± 1.81

 Irritability

1.21 ± 1.82

1.29 ± 2.16

1.10 ± 1.29

0.91 ± 1.59

0.71 ± 1.15

1.27 ± 2.24

 Aberrant motor behavior

0.33 ± 1.63

0.00 ± 0.00

0.80 ± 2.53

0.34 ± 1.15

0.00 ± 0.00

1.00 ± 1.84

Psychosis

0.58 ± 0.78

0.57 ± 0.86

0.60 ± 0.68

0.79 ± 1.19

0.65 ± 0.75

1.06 ± 1.78

 Delusion£

0.21 ± 0.72

0.00 ± 0.00

0.50 ± 1.08

0.63 ± 1.91

0.00 ± 0.00

1.82 ± 2.99

 Hallucination

0.08 ± 0.41

0.00 ± 0.00

0.20 ± 0.63

0.31 ± 1.15

0.10 ± 0.44

0.73 ± 1.85

 Night-time behavior

1.46 ± 2.27

1.71 ± 2.59

1.10 ± 1.79

1.44 ± 1.97

1.86 ± 2.10

0.64 ± 1.43

Affective

0.63 ± 1.10

0.79 ± 1.25

0.40 ± 0.84

1.08 ± 1.41

1.05 ± 1.40

1.14 ± 1.50

 Depression

0.58 ± 1.25

0.57 ± 1.22

0.60 ± 1.35

0.88 ± 1.50

0.76 ± 1.14

1.09 ± 2.07

 Anxiety

0.67 ± 1.52

1.00 ± 1.88

0.20 ± 0.63

1.28 ± 2.33

1.33 ± 2.20

1.18 ± 2.68

Apathy £ǂǂ

0.65 ± 0.89

0.25 ± 0.80

1.20 ± 0.72§§

0.23 ± 0.51

0.21 ± 0.46

0.27 ± 0.61§§

 Apathy ££ǂǂ

0.96 ± 1.43*

0.07 ± 0.27

2.20 ± 1.48§§

0.25 ± 0.62*

0.29 ± 0.72

0.18 ± 0.41§§

 Eating abnormalities

0.33 ± 1.27

0.43 ± 1.60

0.20 ± 0.63

0.22 ± 0.87

0.14 ± 0.66

0.36 ± 1.21

  1. (1) Mean ± SD were shown. (2) Abbreviation: SIVD subcortical ischemic vascular disease, AD Alzheimer’s disease, CDR Clinical Dementia Rating, MMSE Mini-Mental State Examination, CASI Cognitive Abilities Screening Instrument, Sig. Significance.(3) T-test was used to evaluate the group difference and significant difference was defined as p value <0.05. (4) * p < 0.05 on the comparisons between all SIVD patients and all AD patients;# p < 0.05 on the comparisons between SIVD patients with CDR score = 0.5 and AD patients with CDR score = 0.5; § p < 0.05, §§ p < 0.01 on the comparisons between SIVD patients with CDR score = 1 ~ 2 and AD patients with CDR score = 1 ~ 2. (5) £ p < 0.05, ££ p < 0.01, and £££ p < 0.001 on the comparisons between patient with CDR score = 0.5 and with CDR score = 1 ~ 2 among all patients respectively. (6) ǂ p < 0.05 and ǂǂ p < 0.01 on the comparisons between patient with CDR score = 0.5 and with CDR score = 1 ~ 2 in SIVD group respectively. (7) $$$ p < .001 on the comparisons between patient with CDR score = 0.5 and with CDR score = 1 ~ 2 in AD group
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BMC Neurology

ISSN: 1471-2377

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