Comparison of neuropsychiatric symptoms and diffusion tensor imaging correlates among patients with subcortical ischemic vascular disease and Alzheimer’s disease

Table 3 Correlation between Neuropsychiatric Inventory and diffusion tensor imaging parameters within corpus callosum across patient groups

		Fractional Anisotropy			Mean Diffusivity
	Neuropsychiatric Inventory	Genu	Body	Splenium	Genu	Body	Splenium
Total patients (n = 56)	Total score	0.05	−0.20	−0.27*	−0.06	0.32*	0.38^**ǂ
	Hyperactivity	−0.01	−0.20	−0.19	−0.01	0.29*	0.27^*
	Psychosis	0.02	−0.16	−0.34*	0.01	0.27*	0.42^**ǂ
	Affective	0.23	0.06	0.04	−0.20	0.04	0.06
	Apathy	−0.10	−0.26	−0.25	0.04	0.29*	0.27^*
SIVD patients (n = 24)	Total score	0.12	−0.36	−0.40	−0.30	0.37	0.43^*
	Hyperactivity	0.03	−0.31	−0.16	−0.20	0.28	0.19
	Psychosis	0.03	−0.32	−0.49^*ǂǂ	−0.10	0.27	0.42^*ǂ
	Affective	0.33	0.07	0.03	−0.31	0.03	0.06
	Apathy	−0.02	−0.14	−0.32	−0.14	0.17	0.32
AD patients (n = 32)	Total score	0.01	−0.16	−0.24	0.07	0.46**	0.40^*ǂ
	Hyperactivity	−0.02	−0.08	−0.21	0.09	0.36*	0.33
	Psychosis	−0.05	−0.17	−0.34	0.11	0.50**	0.49^**ǂ
	Affective	0.08	−0.10	−0.02	−0.06	0.24	0.14
	Apathy	0.05	−0.24	−0.02	0.01	0.29	0.11

(1) Pearson’s correlation coefficient was used. (2) *p < 0.05, **p < 0.01 on the correlation between NPI and DTI parameters. (3) ^ǂ p < 0.05, ^ǂǂ p < 0.01 on the correlation between NPI and DTI parameters on controlling of age, the total score of CASI, and the CDR score

ISSN: 1471-2377